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DNMT3B DNA methyltransferase 3 beta [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100349823, updated on 20-Feb-2025
Gene symbol
DNMT3B
Gene description
DNA methyltransferase 3 beta
See related
Ensembl:ENSOCUG00000017835
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See DNMT3B in Genome Data Viewer
Location:
chromosome: 11
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 11 NC_091442.1 (25107524..25139056, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 4 NC_067377.1 (14280376..14312146, complement)

Chromosome 11 - NC_091442.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 8 Neighboring gene microtubule associated protein RP/EB family member 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene small nucleolar RNA SNORD105 Neighboring gene COMM domain containing 7 Neighboring gene nucleolar protein 4 like Neighboring gene uncharacterized LOC127490960

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
DNA (cytosine-5)-methyltransferase 3B
Names
DNA (cytosine-5-)-methyltransferase 3 beta
DNA cytosine-5 methyltransferase 3 beta

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091442.1 Reference mOryCun1.1

    Range
    25107524..25139056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_070051927.1 → XP_069908028.1  DNA (cytosine-5)-methyltransferase 3B isoform X3

    UniProtKB/TrEMBL
    A0A5F9DQR2

  2. XM_070051932.1 → XP_069908033.1  DNA (cytosine-5)-methyltransferase 3B isoform X8

    UniProtKB/TrEMBL
    A0A5F9C9G1

  3. XM_070051931.1 → XP_069908032.1  DNA (cytosine-5)-methyltransferase 3B isoform X7

    UniProtKB/TrEMBL
    A0A5F9DDW8

  4. XM_070051929.1 → XP_069908030.1  DNA (cytosine-5)-methyltransferase 3B isoform X5

    UniProtKB/TrEMBL
    A0A5F9DQR2

  5. XM_008256121.4 → XP_008254343.1  DNA (cytosine-5)-methyltransferase 3B isoform X1

    See identical proteins and their annotated locations for XP_008254343.1

    UniProtKB/TrEMBL
    A0A5F9DQR2, G1TEJ2
    Conserved Domains (4) summary
    cd05835
    Location:228 → 314
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PHA03249
    Location:96 → 232
    PHA03249; DNA packaging tegument protein UL25; Provisional
    COG0270
    Location:580 → 762
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd11728
    Location:437 → 556
    ADDz_Dnmt3b; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3b (Dnmt3b)

  6. XM_051845092.2 → XP_051701052.1  DNA (cytosine-5)-methyltransferase 3B isoform X1

    UniProtKB/TrEMBL
    A0A5F9DQR2, G1TEJ2

  7. XM_070051933.1 → XP_069908034.1  DNA (cytosine-5)-methyltransferase 3B isoform X9

    UniProtKB/TrEMBL
    A0A5F9C9G1

  8. XM_070051928.1 → XP_069908029.1  DNA (cytosine-5)-methyltransferase 3B isoform X4

    UniProtKB/TrEMBL
    A0A5F9CSL1

  9. XM_070051926.1 → XP_069908027.1  DNA (cytosine-5)-methyltransferase 3B isoform X2

    UniProtKB/TrEMBL
    A0A5F9DQR2

  10. XM_070051930.1 → XP_069908031.1  DNA (cytosine-5)-methyltransferase 3B isoform X6

    UniProtKB/TrEMBL
    A0A5F9CSL1
Nucleotide Protein
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