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DNMT3B DNA methyltransferase 3 beta [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100349823, updated on 3-Apr-2017

Summary

Gene symbol
DNMT3B
Gene description
DNA methyltransferase 3 beta
See related
Ensembl:ENSOCUG00000017835
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs

Genomic context

See DNMT3B in Genome Data Viewer
Location:
chromosome: 4
Exon count:
25
Annotation release Status Assembly Chr Location
102 current OryCun2.0 (GCF_000003625.3) 4 NC_013672.1 (6629783..6661578, complement)

Chromosome 4 - NC_013672.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 8 Neighboring gene microtubule associated protein RP/EB family member 1 Neighboring gene COMM domain containing 7 Neighboring gene uncharacterized LOC108176610 Neighboring gene nucleolar protein 4 like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_013672.1 Chromosome 4 Reference OryCun2.0 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Cysteine and methionine metabolism, organism-specific biosystem (from KEGG)
    Cysteine and methionine metabolism, organism-specific biosystemCysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted f...
  • Cysteine and methionine metabolism, conserved biosystem (from KEGG)
    Cysteine and methionine metabolism, conserved biosystemCysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted f...
  • Metabolic pathways, organism-specific biosystem (from KEGG)
    Metabolic pathways, organism-specific biosystem
    Metabolic pathways
  • Methionine degradation, organism-specific biosystem (from KEGG)
    Methionine degradation, organism-specific biosystemPathway module; Nucleotide and amino acid metabolism; Cysteine and methionine metabolism
  • Methionine degradation, conserved biosystem (from KEGG)
    Methionine degradation, conserved biosystemPathway module; Nucleotide and amino acid metabolism; Cysteine and methionine metabolism
  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...

General protein information

Preferred Names
DNA (cytosine-5)-methyltransferase 3B
Names
DNA (cytosine-5-)-methyltransferase 3 beta
DNA cytosine-5 methyltransferase 3 beta

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Oryctolagus cuniculus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OryCun2.0 Primary Assembly

Genomic

  1. NC_013672.1 Reference OryCun2.0 Primary Assembly

    Range
    6629783..6661578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008256121.2XP_008254343.1  DNA (cytosine-5)-methyltransferase 3B isoform X2

    See identical proteins and their annotated locations for XP_008254343.1

    Conserved Domains (4) summary
    cd05835
    Location:228314
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PHA03249
    Location:96232
    PHA03249; DNA packaging tegument protein UL25; Provisional
    COG0270
    Location:580762
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd11728
    Location:437556
    ADDz_Dnmt3b; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3b (Dnmt3b)
  2. XM_008256122.2XP_008254344.1  DNA (cytosine-5)-methyltransferase 3B isoform X9

    Conserved Domains (4) summary
    cd05835
    Location:228314
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PHA03249
    Location:96232
    PHA03249; DNA packaging tegument protein UL25; Provisional
    COG0270
    Location:560742
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd11728
    Location:417536
    ADDz_Dnmt3b; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3b (Dnmt3b)
  3. XM_002710806.3XP_002710852.1  DNA (cytosine-5)-methyltransferase 3B isoform X2

    See identical proteins and their annotated locations for XP_002710852.1

    Related
    ENSOCUP00000015318.2, ENSOCUT00000017835.2
    Conserved Domains (4) summary
    cd05835
    Location:228314
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    PHA03249
    Location:96232
    PHA03249; DNA packaging tegument protein UL25; Provisional
    COG0270
    Location:580762
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd11728
    Location:437556
    ADDz_Dnmt3b; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3b (Dnmt3b)
  4. XM_017341693.1XP_017197182.1  DNA (cytosine-5)-methyltransferase 3B isoform X4

  5. XM_017341696.1XP_017197185.1  DNA (cytosine-5)-methyltransferase 3B isoform X7

  6. XM_017341691.1XP_017197180.1  DNA (cytosine-5)-methyltransferase 3B isoform X1

  7. XM_017341692.1XP_017197181.1  DNA (cytosine-5)-methyltransferase 3B isoform X3

  8. XM_017341694.1XP_017197183.1  DNA (cytosine-5)-methyltransferase 3B isoform X5

  9. XM_017341697.1XP_017197186.1  DNA (cytosine-5)-methyltransferase 3B isoform X8

  10. XM_017341695.1XP_017197184.1  DNA (cytosine-5)-methyltransferase 3B isoform X6

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