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GSK3B glycogen synthase kinase 3 beta [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100348842, updated on 17-Dec-2024
Gene symbol
GSK3B
Gene description
glycogen synthase kinase 3 beta
See related
Ensembl:ENSOCUG00000014932
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See GSK3B in Genome Data Viewer
Location:
chromosome: 4
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 4 NC_091435.1 (76332370..76550971, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 14 NC_067387.1 (99809812..100038257)

Chromosome 4 - NC_091435.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 91 Neighboring gene eukaryotic initiation factor 4A-II pseudogene Neighboring gene nuclear receptor subfamily 1 group I member 2 Neighboring gene transcription factor SOX-4 Neighboring gene microRNA mir-6529 Neighboring gene G protein-coupled receptor 156 Neighboring gene transcription initiation factor TFIID subunit 12 pseudogene

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation. Zhang L, et al. Cell Res, 2014 Jun. PMID 24777252, Free PMC Article
  2. Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity. Lubas WA, et al. J Biol Chem, 2000 Apr 14. PMID 10753899
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau-protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
glycogen synthase kinase-3 beta

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091435.1 Reference mOryCun1.1

    Range
    76332370..76550971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002716661.5 → XP_002716707.1  glycogen synthase kinase-3 beta isoform X2

    See identical proteins and their annotated locations for XP_002716707.1

    UniProtKB/TrEMBL
    A0A5F9DFZ1, A0A5F9DUX8
    Related
    ENSOCUP00000049340.1
    Conserved Domains (1) summary
    cd14137
    Location:51 → 343
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  2. XM_070072184.1 → XP_069928285.1  glycogen synthase kinase-3 beta isoform X6

    UniProtKB/TrEMBL
    G1T8E2

  3. XM_002716660.5 → XP_002716706.1  glycogen synthase kinase-3 beta isoform X1

    UniProtKB/TrEMBL
    A0A5F9CM08, G1T8E2
    Related
    ENSOCUP00000034516.1
    Conserved Domains (2) summary
    cd14137
    Location:51 → 356
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    pfam00069
    Location:56 → 353
    Pkinase; Protein kinase domain

  4. XM_008266875.4 → XP_008265097.1  glycogen synthase kinase-3 beta isoform X5

    UniProtKB/TrEMBL
    G1T8E2
    Conserved Domains (2) summary
    cd14137
    Location:51 → 356
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    pfam00069
    Location:56 → 353
    Pkinase; Protein kinase domain

  5. XM_070072185.1 → XP_069928286.1  glycogen synthase kinase-3 beta isoform X7

    UniProtKB/TrEMBL
    A0A5F9DFZ1

  6. XM_008266873.4 → XP_008265095.1  glycogen synthase kinase-3 beta isoform X3

    UniProtKB/TrEMBL
    A0A5F9DFZ1
    Related
    ENSOCUP00000045109.1
    Conserved Domains (2) summary
    cd14137
    Location:32 → 337
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    pfam00069
    Location:37 → 334
    Pkinase; Protein kinase domain

  7. XM_008266874.4 → XP_008265096.1  glycogen synthase kinase-3 beta isoform X4

    UniProtKB/TrEMBL
    A0A5F9DFZ1
    Conserved Domains (2) summary
    cd14137
    Location:30 → 335
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    pfam00069
    Location:35 → 332
    Pkinase; Protein kinase domain
Nucleotide Protein
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