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IL18RAP interleukin 18 receptor accessory protein [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100343288, updated on 17-Dec-2024

Summary

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Gene symbol
IL18RAP
Gene description
interleukin 18 receptor accessory protein
See related
Ensembl:ENSOCUG00000006067
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See IL18RAP in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 2 NC_091433.1 (106225566..106255734, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (90398771..90428911, complement)

Chromosome 2 - NC_091433.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene solute carrier family 9 member A4 Neighboring gene interleukin 18 receptor 1 Neighboring gene interleukin 1 receptor like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death. Yoshida T, et al. J Mol Cell Cardiol, 2014 Oct. PMID 25108227, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-1 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-18 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-18-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-18 receptor accessory protein
NP_001315997.1
XP_008251419.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001329068.1 → NP_001315997.1  interleukin-18 receptor accessory protein precursor

    Status: PROVISIONAL

    Source sequence(s)
    JF271682
    UniProtKB/TrEMBL
    G3EPL1, G3EPL2
    Conserved Domains (5) summary
    PHA02785
    Location:42 → 247
    PHA02785; IL-beta-binding protein; Provisional
    pfam07679
    Location:224 → 326
    I-set; Immunoglobulin I-set domain
    pfam01582
    Location:384 → 532
    TIR; TIR domain
    pfam13895
    Location:151 → 213
    Ig_2; Immunoglobulin domain
    cl11960
    Location:224 → 322
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091433.1 Reference mOryCun1.1

    Range
    106225566..106255734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008253197.4 → XP_008251419.3  interleukin-18 receptor accessory protein isoform X1

    UniProtKB/TrEMBL
    G3EPL1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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