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FYN FYN proto-oncogene, Src family tyrosine kinase [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100339741, updated on 2-Dec-2024
Gene symbol
FYN
Gene description
FYN proto-oncogene, Src family tyrosine kinase
See related
Ensembl:ENSOCUG00000015784
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See FYN in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 5 NC_091436.1 (59712280..59935011)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 12 NC_067385.1 (56220111..56450042)

Chromosome 5 - NC_091436.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC127492990 Neighboring gene cellular communication network factor 6 Neighboring gene uncharacterized LOC138849616 Neighboring gene uncharacterized LOC138849617

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tyrosine-protein kinase Fyn
Names
FYN oncogene related to SRC, FGR, YES

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091436.1 Reference mOryCun1.1

    Range
    59712280..59935011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008263382.4 → XP_008261604.1  tyrosine-protein kinase Fyn isoform X1

    See identical proteins and their annotated locations for XP_008261604.1

    UniProtKB/TrEMBL
    G1TA73
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

  2. XM_002714927.5 → XP_002714973.1  tyrosine-protein kinase Fyn isoform X2

    UniProtKB/TrEMBL
    A0A5F9CRM1
    Related
    ENSOCUP00000036339.1
    Conserved Domains (4) summary
    cd10368
    Location:145 → 245
    SH2_Src_Fyn; Src homology 2 (SH2) domain found in Fyn
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:258 → 531
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
    pfam07714
    Location:268 → 517
    Pkinase_Tyr; Protein tyrosine kinase

  3. XM_002714925.5 → XP_002714971.1  tyrosine-protein kinase Fyn isoform X1

    See identical proteins and their annotated locations for XP_002714971.1

    UniProtKB/TrEMBL
    G1TA73
    Related
    ENSOCUP00000013559.2
    Conserved Domains (3) summary
    cd10418
    Location:145 → 245
    SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
    cd12006
    Location:85 → 140
    SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
    cd05070
    Location:261 → 534
    PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
Nucleotide Protein
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