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rap1gds1 RAP1, GTP-GDP dissociation stimulator 1 [ Danio rerio (zebrafish) ]

Gene ID: 100334870, updated on 9-Sep-2025
Official Symbol
rap1gds1provided by ZNC
Official Full Name
RAP1, GTP-GDP dissociation stimulator 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-101230-2
See related
Ensembl:ENSDARG00000073741 AllianceGenome:ZFIN:ZDB-GENE-101230-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in animal organ development. Predicted to act upstream of or within positive regulation of GTPase activity. Predicted to be located in endoplasmic reticulum and mitochondrion. Predicted to be active in cytosol. Orthologous to human RAP1GDS1 (Rap1 GTPase-GDP dissociation stimulator 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See rap1gds1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 7 NC_133182.1 (75052998..75125317)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 7 NC_007118.7 (69528906..69583245)

Chromosome 7 - NC_133182.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene spermatogenesis associated 6-like Neighboring gene solute carrier family 1 member 1 Neighboring gene uncharacterized LOC137496241 Neighboring gene tetraspanin 5a Neighboring gene bone morphogenetic protein 7

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Regulation of cytochrome P450 expression in a novel liver cell line from zebrafish (Brachydanio rerio). Miranda CL, et al. Arch Biochem Biophys, 1993 Sep. PMID 8373170
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
rap1 GTPase-GDP dissociation stimulator 1

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RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133182.1 Reference GRCz12tu Primary Assembly

    Range
    75052998..75125317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073907558.1 → XP_073763659.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q945

  2. XM_073907560.1 → XP_073763661.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X3

  3. XM_073907559.1 → XP_073763660.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X2

  4. XM_073907561.1 → XP_073763662.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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