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gdf5 growth differentiation factor 5 [ Danio rerio (zebrafish) ]

Gene ID: 100334210, updated on 1-Aug-2018

Summary

Official Symbol
gdf5provided by ZNC
Official Full Name
growth differentiation factor 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-990415-39
See related
Ensembl:ENSDARG00000002760 Vega:OTTDARG00000034417
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
ctc; bmp14; e1gdf5; contact
Orthologs

Genomic context

See gdf5 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (52637314..52644474, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (52639130..52645729, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83, member C Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 1 Neighboring gene syndecan 4 Neighboring gene uncharacterized LOC108190448 Neighboring gene oxidative stress responsive serine-rich 1

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
growth factor activity IEA
Inferred from Electronic Annotation
more info
 
transforming growth factor beta receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
BMP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SMAD protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of pathway-restricted SMAD protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
growth differentiation factor 5; growth/differentiation factor 5

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    52637314..52644474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002662541.5XP_002662587.1  growth/differentiation factor 5

    UniProtKB/TrEMBL
    F1QK08
    Related
    ENSDARP00000003126.3, OTTDARP00000038195, ENSDART00000015051.5
    Conserved Domains (2) summary
    pfam00019
    Location:371473
    TGF_beta; Transforming growth factor beta like domain
    pfam00688
    Location:138320
    TGFb_propeptide; TGF-beta propeptide
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