U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mir1896 microRNA 1896 [ Mus musculus (house mouse) ]

Gene ID: 100316752, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Mir1896provided by MGI
Official Full Name
microRNA 1896provided by MGI
Primary source
MGI:MGI:3811418
See related
Ensembl:ENSMUSG00000084590 miRBase:MI0008322; AllianceGenome:MGI:3811418
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mirn1896; mmu-mir-1896
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Mir1896 in Genome Data Viewer
Location:
13 A3.1; 13 7.8 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (21629330..21629410)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21445160..21445240)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger with KRAB and SCAN domains 3 Neighboring gene STARR-seq mESC enhancer starr_33849 Neighboring gene STARR-positive B cell enhancer ABC_E10783 Neighboring gene microRNA 6942 Neighboring gene piggyBac transposable element derived 1 Neighboring gene RIKEN cDNA 4930470G03 gene Neighboring gene zinc finger and SCAN domain containing 26 Neighboring gene STARR-positive B cell enhancer ABC_E11532 Neighboring gene NFKB activating protein-like Neighboring gene zinc finger with KRAB and SCAN domains 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling. Liu X, et al. Glia, 2019 Jan. PMID 30294880
  2. MicroRNA-encoding long non-coding RNAs. He S, et al. BMC Genomics, 2008 May 21. PMID 18492288, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mir1896 and miR-409-3p collectively promote the production of inflammatory cytokines in reactive astrocytes through the SOCS3/STAT3 pathway.
    Title: MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Other Names

  • microRNA mir-1896

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to interleukin-17 IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cytokine production IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gene expression IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_035441.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    BX001068
    Related
    ENSMUST00000122641.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    21629330..21629410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.