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MIR423 microRNA mir-423 [ Pan troglodytes (chimpanzee) ]

Gene ID: 100316165, updated on 9-Jul-2025
Gene symbol
MIR423
Gene description
microRNA mir-423
See related
miRBase:MI0008663
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
ptr-mir-423
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See MIR423 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (37459523..37459615, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (35643980..35644072, complement)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene bleomycin hydrolase Neighboring gene solute carrier family 6 member 4 Neighboring gene nuclear speckle splicing regulatory protein 1 Neighboring gene uncharacterized LOC107969205 Neighboring gene syntaxin-18-like Neighboring gene EF-hand calcium binding domain 5 Neighboring gene small nucleolar RNA U13 Neighboring gene slingshot protein phosphatase 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Computational identification of novel microRNA homologs in the chimpanzee genome. Baev V, et al. Comput Biol Chem, 2009 Feb. PMID 18760970
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Other Names

  • microRNA 423

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_035795.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JAQQLN020000019
    Related
    ENSPTRT00045077225.1

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    37459523..37459615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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