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MIR221 microRNA mir-221 [ Equus caballus (horse) ]

Gene ID: 100314997, updated on 15-Aug-2024

Summary

Gene symbol
MIR221
Gene description
microRNA mir-221
See related
Ensembl:ENSECAG00000025993 miRBase:MI0012951
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
eca-mir-221
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR221 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) X NC_009175.3 (38513896..38514005, complement)

Chromosome X - NC_009175.3Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase Mu 1-like Neighboring gene uncharacterized LOC111771621 Neighboring gene microRNA mir-222 Neighboring gene uncharacterized LOC111771569

Genomic regions, transcripts, and products

Genomic Sequence:
NC_009175.3 Chromosome X Reference EquCab3.0 Primary Assembly

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033079.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000001
    Related
    ENSECAT00000028005.2

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009175.3 Reference EquCab3.0 Primary Assembly

    Range
    38513896..38514005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)