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MIR15A microRNA mir-15a [ Equus caballus (horse) ]

Gene ID: 100314872, updated on 18-Dec-2024
Gene symbol
MIR15A
Gene description
microRNA mir-15a
See related
Ensembl:ENSECAG00000025521 miRBase:MI0012829
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
eca-mir-15a
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See MIR15A in Genome Data Viewer
Location:
chromosome: 17
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_12 current TB-T2T (GCF_041296265.1) 17 NC_091700.1 (41619099..41619155)
RS_2024_08 previous assembly EquCab3.0 (GCF_002863925.1) 17 NC_009160.3 (21041772..21041828)

Chromosome 17 - NC_091700.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111768581 Neighboring gene uncharacterized LOC102150380 Neighboring gene uncharacterized LOC138918395 Neighboring gene microRNA mir-16-2 Neighboring gene potassium channel regulator

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Thoroughbred Stallion gene expression
  • BioProject: PRJEB53382
  • Analysis date: Mon Jan 06 09:53:19 2025

Related articles in PubMed

  1. In silico detection and characteristics of novel microRNA genes in the Equus caballus genome using an integrated ab initio and comparative genomic approach. Zhou M, et al. Genomics, 2009 Aug. PMID 19406225
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Other Names

  • microRNA 15a

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_032957.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000018
    Related
    ENSECAT00000027533.2

RefSeqs of Annotated Genomes: GCF_041296265.1-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TB-T2T Primary Assembly

Genomic

  1. NC_091700.1 Reference TB-T2T Primary Assembly

    Range
    41619099..41619155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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