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Mir299b microRNA 299B [ Rattus norvegicus (Norway rat) ]

Gene ID: 100314064, updated on 3-May-2025
Official Symbol
Mir299bprovided by RGD
Official Full Name
microRNA 299Bprovided by RGD
Primary source
RGD:2325540
See related
miRBase:MI0000970; AllianceGenome:RGD:2325540
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mir299; Mir299a; rno-mir-299; rno-mir-299a
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See Mir299b in Genome Data Viewer
Location:
6q32
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (134545069..134545131)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (128723664..128723726)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (133859324..133859386)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102555254 Neighboring gene microRNA 299B Neighboring gene microRNA 379 Neighboring gene microRNA 3579 Neighboring gene microRNA 411 Neighboring gene microRNA 380 Neighboring gene microRNA 323

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Embryonic stem cell-specific MicroRNAs. Houbaviy HB, et al. Dev Cell, 2003 Aug. PMID 12919684
  2. Small RNA expression and strain specificity in the rat. Linsen SE, et al. BMC Genomics, 2010 Apr 19. PMID 20403161, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Other Names

  • microRNA 299
  • microRNA mir-299
  • microRNA mir-299a

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in energy homeostasis ISO
Inferred from Sequence Orthology
more info
  

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_031943.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000006

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    134545069..134545131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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