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Mir219a1 microRNA 219a-1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100314058, updated on 29-Nov-2020


Official Symbol
Mir219a1provided by RGD
Official Full Name
microRNA 219a-1provided by RGD
Primary source
See related
Ensembl:ENSRNOG00000035653 miRBase:MI0000959
Gene type
RefSeq status
Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mir219-1; rno-mir-219-1; rno-mir-219a-1
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Genomic context

See Mir219a1 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3816158..3816267, complement)
106 current Rn_Celera (GCF_000002265.2) 20 AC_000088.1 (6429872..6429981)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 20 NC_005119.3 (5895489..5895598, complement)

Chromosome 20 - NC_005119.4Genomic Context describing neighboring genes Neighboring gene class I histocompatibility antigen, Non-RT1.A alpha-1 chain-like Neighboring gene ring finger protein 1 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 8 Neighboring gene solute carrier family 39 member 7 Neighboring gene retinoid X receptor beta

Genomic regions, transcripts, and products


GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information


Other Names

  • microRNA 219-1
  • microRNA mir-219-1

Gene Ontology Provided by RGD

Process Evidence Code Pubs
cellular response to growth factor stimulus ISO
Inferred from Sequence Orthology
more info
cellular response to leukemia inhibitory factor ISO
Inferred from Sequence Orthology
more info
negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
positive regulation of oligodendrocyte differentiation ISO
Inferred from Sequence Orthology
more info
regulation of myelination ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
RISC complex ISO
Inferred from Sequence Orthology
more info

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_031932.1 RNA Sequence


    Source sequence(s)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly


  1. NC_005119.4 Reference Rnor_6.0 Primary Assembly

    3816158..3816267 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera


  1. AC_000088.1 Alternate Rn_Celera

    GenBank, FASTA, Sequence Viewer (Graphics)
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