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MIR2114 microRNA 2114 [ Homo sapiens (human) ]

Gene ID: 100313839, updated on 13-May-2022

Summary

Official Symbol
MIR2114provided by HGNC
Official Full Name
microRNA 2114provided by HGNC
Primary source
HGNC:HGNC:37308
See related
Ensembl:ENSG00000252454 miRBase:MI0010633; AllianceGenome:HGNC:37308
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR2114 in Genome Data Viewer
Location:
Xq28
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (150228004..150228083)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (148495578..148495657)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (149396239..149396318)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene EOLA2 divergent transcript Neighboring gene nucleolar protein 11 pseudogene Neighboring gene X-ray repair cross complementing 6 pseudogene 2 Neighboring gene mastermind like domain containing 1 Neighboring gene uncharacterized LOC124905223

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_031748.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC235697
    Related
    ENST00000516645.3

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    150228004..150228083
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    148495578..148495657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)