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MIR141 microRNA mir-141 [ Bos taurus (domestic cattle) ]

Gene ID: 100313001, updated on 1-Feb-2025

Summary

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Gene symbol
MIR141
Gene description
microRNA mir-141
See related
miRBase:MI0009742
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
bta-mir-141
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See MIR141 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (103498826..103498915, complement)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene lysophosphatidylcholine acyltransferase 3 Neighboring gene EMG1 N1-specific pseudouridine methyltransferase Neighboring gene small nucleolar RNA U89 Neighboring gene uncharacterized LOC112446758 Neighboring gene prohibitin 2 Neighboring gene microRNA mir-200c Neighboring gene protein tyrosine phosphatase non-receptor type 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Annotation of 390 bovine miRNA genes by sequence similarity with other species. Strozzi F, et al. Anim Genet, 2009 Feb. PMID 18945293
  2. miRNAminer: a tool for homologous microRNA gene search. Artzi S, et al. BMC Bioinformatics, 2008 Jan 23. PMID 18215311, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Other Names

  • microRNA 141

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_030864.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000005

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    103498826..103498915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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