ANKRD61 ankyrin repeat domain 61 [Homo sapiens (human)] - Gene

Summary

Official Symbol: ANKRD61provided by HGNC
Official Full Name: ankyrin repeat domain 61provided by HGNC
Primary source: HGNC:HGNC:22467
See related: Ensembl:ENSG00000157999 AllianceGenome:HGNC:22467
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis (RPKM 3.5), bone marrow (RPKM 1.7) and 12 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 7p22.1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_03	current	GRCh38.p14 (GCF_000001405.40)	7	NC_000007.14 (6031376..6036552)
RS_2023_03	current	T2T-CHM13v2.0 (GCF_009914755.1)	7	NC_060931.1 (6149151..6154327)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	7	NC_000007.13 (6071007..6076183)

Chromosome 7 - NC_000007.14 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Gene Ontology Provided by GOA

Component	Evidence Code	Pubs
located_in nucleoplasm	IDA Inferred from Direct Assay more info

General protein information

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Preferred Names: ankyrin repeat domain-containing protein 61

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001271700.2 → NP_001258629.1 ankyrin repeat domain-containing protein 61

See identical proteins and their annotated locations for NP_001258629.1

Status: VALIDATED

Source sequence(s)

AC005995, AI221268

Consensus CDS

CCDS64590.1

UniProtKB/Swiss-Prot

A6NGH8

Related

ENSP00000386502.1, ENST00000409061.2

Conserved Domains (5) summary

cd00204
Location:166 → 298

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:172 → 275

Ank_2; Ankyrin repeats (3 copies)

pfam13857
Location:263 → 317

Ank_5; Ankyrin repeats (many copies)

sd00045
Location:169 → 198

ANK; ANK repeat [structural motif]

cl02529
Location:32 → 115

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...