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mir126b microRNA mir-126b [ Danio rerio (zebrafish) ]

Gene ID: 100310774, updated on 27-Mar-2024


Gene symbol
Gene description
microRNA mir-126b
See related
Ensembl:ENSDARG00000098981 miRBase:MI0010848
Gene type
RefSeq status
Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mir-126b; dre-mir-126b
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See mir126b in Genome Data Viewer
chromosome: 21
Exon count:
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (7240227..7240329, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (7678736..7678838, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene divergent protein kinase domain 1B Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) Neighboring gene EGF-like-domain, multiple 7 Neighboring gene adaptor related protein complex 3 subunit beta 1a Neighboring gene uncharacterized LOC110438212

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_030659.1 RNA Sequence


    Source sequence(s)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly


  1. NC_007132.7 Reference GRCz11 Primary Assembly

    7240227..7240329 complement
    GenBank, FASTA, Sequence Viewer (Graphics)