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FTX FTX transcript, XIST regulator [ Homo sapiens (human) ]

Gene ID: 100302692, updated on 22-Aug-2021

Summary

Official Symbol
FTXprovided by HGNC
Official Full Name
FTX transcript, XIST regulatorprovided by HGNC
Primary source
HGNC:HGNC:37190
See related
Ensembl:ENSG00000230590 MIM:300936
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LINC00182; MIR374AHG; NCRNA00182
Summary
This gene is located upstream of XIST, within the X-inactivation center (XIC). It produces a spliced long non-coding RNA that is thought to positively regulate the expression of XIST, which is essential for the initiation and spread of X-inactivation. [provided by RefSeq, May 2015]
Expression
Ubiquitous expression in ovary (RPKM 3.1), thyroid (RPKM 2.1) and 25 other tissues See more
Orthologs
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Genomic context

See FTX in Genome Data Viewer
Location:
Xq13.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (74028136..74293574, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (73247971..73513409, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene TSIX transcript, XIST antisense RNA Neighboring gene X inactive specific transcript Neighboring gene FXYD domain containing ion transport regulator 6 pseudogene 3 Neighboring gene JPX transcript, XIST activator Neighboring gene ribosomal protein SA pseudogene 14 Neighboring gene SHISA5 pseudogene 2 Neighboring gene AARSD1 pseudogene 1 Neighboring gene ubiquitin like with PHD and ring finger domains 2 pseudogene 1 Neighboring gene DEAD-box helicase 3 pseudogene 1 Neighboring gene DEAD-box helicase 3 pseudogene 2 Neighboring gene ATP5MK pseudogene 1 Neighboring gene makorin ring finger protein 5, pseudogene Neighboring gene RAB11 family interacting protein 1 pseudogene 1 Neighboring gene BMP2 inducible kinase like (pseudogene) Neighboring gene microRNA 374b Neighboring gene microRNA 374c Neighboring gene microRNA 421 Neighboring gene RNA, 7SL, cytoplasmic 648, pseudogene Neighboring gene microRNA 374a Neighboring gene microRNA 545 Neighboring gene zinc finger CCHC-type containing 13 Neighboring gene NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • FTX transcript, XIST regulator (non-protein coding)
  • five prime to XIST
  • mir-374a-545 cluster host gene (non-protein coding)

Clone Names

  • FLJ18387

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_028379.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004386, AL139400
    Related
    ENST00000602812.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    74028136..74293574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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