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MIR1289-2 microRNA 1289-2 [ Homo sapiens (human) ]

Gene ID: 100302134, updated on 10-Oct-2023


Official Symbol
MIR1289-2provided by HGNC
Official Full Name
microRNA 1289-2provided by HGNC
Primary source
See related
Ensembl:ENSG00000221287 miRBase:MI0006351; AllianceGenome:HGNC:35282
Gene type
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIRN1289-2; hsa-mir-1289-2
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR1289-2 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (133427596..133427706, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (133947311..133947421, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (132763288..132763398, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene follistatin like 4 Neighboring gene uncharacterized LOC124901068 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132699589-132700090 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr5:132700914-132701437 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr5:132706200-132707399 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132736128-132736662 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132737352-132738266 Neighboring gene uncharacterized CTB-3M24.3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23104 Neighboring gene Sharpr-MPRA regulatory region 9043 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:132793114-132794313 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:132817823-132818324 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:132818325-132818824 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:132860511-132861011 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16346 Neighboring gene MPRA-validated peak5467 silencer Neighboring gene uncharacterized LOC124901066 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:132918472-132919164 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:132919165-132919856 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr5:132938505-132939090 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16347 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:133019878-133020042 Neighboring gene dnaJ homolog subfamily C member 24-like

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_031621.1 RNA Sequence


    Source sequence(s)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    133427596..133427706 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060929.1 Alternate T2T-CHM13v2.0

    133947311..133947421 complement
    GenBank, FASTA, Sequence Viewer (Graphics)