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PRSS46P serine protease 46, pseudogene [ Homo sapiens (human) ]

Gene ID: 100287362, updated on 9-Jun-2025
Official Symbol
PRSS46Pprovided by HGNC
Official Full Name
serine protease 46, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:37325
See related
Ensembl:ENSG00000293416 AllianceGenome:HGNC:37325
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRSS46; TESSP6
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Biased expression in testis (RPKM 2.7), thyroid (RPKM 0.5) and 2 other tissues See more
Orthologs
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See PRSS46P in Genome Data Viewer
Location:
3p21.31
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (46719583..46736427, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (46735668..46752512, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (46761073..46777917, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14292 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46736106-46736895 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46737985-46738484 Neighboring gene transmembrane inner ear Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:46747903-46748660 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19798 Neighboring gene serine protease 50 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14293 Neighboring gene serine protease 45, pseudogene Neighboring gene serine protease 43, pseudogene

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Other Names

  • protease, serine 46, pseudogene
  • putative serine protease 46
  • testis serine protease 6

Clone Names

  • FLJ35279, FLJ40347

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_147121.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC134504
    Related
    ENST00000463091.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    46719583..46736427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    46735668..46752512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001205271.1: Suppressed sequence

    Description
    NM_001205271.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.