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nrg2b neuregulin 2b [ Danio rerio (zebrafish) ]

Gene ID: 100270726, updated on 12-Aug-2018

Summary

Official Symbol
nrg2bprovided by ZNC
Official Full Name
neuregulin 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090205-2
See related
Ensembl:ENSDARG00000086585 Vega:OTTDARG00000041990
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio

Genomic context

See nrg2b in Genome Data Viewer
Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8274118..8437933)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (7968032..8131819)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene pleckstrin and Sec7 domain containing 2 Neighboring gene purine-rich element binding protein Ab Neighboring gene si:dkey-160o24.3 Neighboring gene eukaryotic translation initiation factor 1A domain containing

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pro-neuregulin-2, membrane-bound isoform
Names
neuregulin 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145091.2NP_001138563.1  pro-neuregulin-2, membrane-bound isoform

    See identical proteins and their annotated locations for NP_001138563.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ593494
    UniProtKB/TrEMBL
    B9VQL5
    Related
    ENSDARP00000109596.1, OTTDARP00000047797, ENSDART00000127494.3, OTTDART00000060528
    Conserved Domains (4) summary
    PHA02887
    Location:86177
    PHA02887; EGF-like protein; Provisional
    pfam07679
    Location:37123
    I-set; Immunoglobulin I-set domain
    pfam02158
    Location:195584
    Neuregulin; Neuregulin family
    cl11960
    Location:51121
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    8274118..8437933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307712.3XP_009305987.1  pro-neuregulin-2, membrane-bound isoform isoform X2

    Conserved Domains (4) summary
    PHA03099
    Location:244340
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam07679
    Location:143229
    I-set; Immunoglobulin I-set domain
    pfam02158
    Location:301690
    Neuregulin; Neuregulin family
    cl11960
    Location:157227
    Ig; Immunoglobulin domain
  2. XM_009307713.3XP_009305988.1  pro-neuregulin-2, membrane-bound isoform isoform X3

    Conserved Domains (4) summary
    PHA03099
    Location:244336
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam07679
    Location:143229
    I-set; Immunoglobulin I-set domain
    pfam02158
    Location:297686
    Neuregulin; Neuregulin family
    cl11960
    Location:157227
    Ig; Immunoglobulin domain
  3. XM_005157119.4XP_005157176.1  pro-neuregulin-2, membrane-bound isoform isoform X1

    UniProtKB/TrEMBL
    E7FGA4
    Related
    ENSDARP00000108874.2, OTTDARP00000047796, ENSDART00000129055.3
    Conserved Domains (4) summary
    PHA02887
    Location:192283
    PHA02887; EGF-like protein; Provisional
    pfam07679
    Location:143229
    I-set; Immunoglobulin I-set domain
    pfam02158
    Location:301690
    Neuregulin; Neuregulin family
    cl11960
    Location:157227
    Ig; Immunoglobulin domain
  4. XM_005157120.4XP_005157177.1  pro-neuregulin-2, membrane-bound isoform isoform X4

    Conserved Domains (4) summary
    PHA03099
    Location:244332
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam07679
    Location:143229
    I-set; Immunoglobulin I-set domain
    pfam02158
    Location:293682
    Neuregulin; Neuregulin family
    cl11960
    Location:157227
    Ig; Immunoglobulin domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394891.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    17256..64485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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