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Gon7 GON7 subunit of KEOPS complex [ Mus musculus (house mouse) ]

Gene ID: 100233175, updated on 26-Sep-2022


Official Symbol
Gon7provided by MGI
Official Full Name
GON7 subunit of KEOPS complexprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000091931 AllianceGenome:MGI:4845848
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of EKC/KEOPS complex. Orthologous to human GON7 (GON7 subunit of KEOPS complex). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in CNS E11.5 (RPKM 14.8), CNS E14 (RPKM 10.5) and 28 other tissues See more
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Genomic context

See Gon7 in Genome Data Viewer
12; 12 E
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (102719534..102724069, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (102753275..102757810, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene 20604 Neighboring gene modulator of apoptosis 1 Neighboring gene lysosomal enzyme trafficking factor Neighboring gene ubiquitin protein ligase E3 component n-recognin 7 (putative) Neighboring gene BTB (POZ) domain containing 7 Neighboring gene cytochrome c oxidase subunit 7C, mitochondrial pseudogene

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Readthrough Gm20604

Readthrough gene: Gm20604, Included gene: Moap1

Potential readthrough

Included gene: Itpk1


Clone Names

  • MGC25937, MGC60472

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in tRNA threonylcarbamoyladenosine modification ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
part_of EKC/KEOPS complex IBA
Inferred from Biological aspect of Ancestor
more info
part_of EKC/KEOPS complex ISO
Inferred from Sequence Orthology
more info
located_in cytosol ISO
Inferred from Sequence Orthology
more info
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
located_in nucleus ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
EKC/KEOPS complex subunit GON7
GON7, KEOPS complex subunit homolog
uncharacterized protein C14orf142 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142938.1NP_001136410.1  EKC/KEOPS complex subunit GON7

    See identical proteins and their annotated locations for NP_001136410.1

    Status: VALIDATED

    Source sequence(s)
    AC132315, AK010878
    Consensus CDS
    ENSMUSP00000136425.2, ENSMUST00000173969.2
    Conserved Domains (1) summary
    DUF4611; Domain of unknown function (DUF4611)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000078.7 Reference GRCm39 C57BL/6J

    102719534..102724069 complement
    GenBank, FASTA, Sequence Viewer (Graphics)