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HTT huntingtin [ Ovis aries (sheep) ]

Gene ID: 100216476, updated on 10-Feb-2026
Gene symbol
HTT
Gene description
huntingtin
See related
Ensembl:ENSOARG00020051571
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See HTT in Genome Data Viewer
Location:
chromosome: 6
Exon count:
71
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 6 NC_056059.1 (116327379..116449465, complement)

Chromosome 6 - NC_056059.1Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 12 Neighboring gene basic salivary proline-rich protein 1-like Neighboring gene Myb/SANT DNA binding domain containing 1 Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene NOP14 nucleolar protein

Genomic Sequence:
NC_056059.1 Chromosome 6 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Ovis aries Rambouillet Genome sequencing and assembly
  • BioProject: PRJNA414087
  • Analysis date: Thu Jan 09 10:41:41 2025

Related articles in PubMed

  1. An ovine transgenic Huntington's disease model. Jacobsen JC, et al. Hum Mol Genet, 2010 May 15. PMID 20154343, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in microtubule-based transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
huntingtin

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142638.1 → NP_001136110.1  huntingtin

    See identical proteins and their annotated locations for NP_001136110.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ457100
    UniProtKB/TrEMBL
    A0A6P9FQH6, A0AC11C8R3, B7U9A4
    Related
    ENSOARP00020076319.1, ENSOART00020150469.1
    Conserved Domains (2) summary
    pfam12372
    Location:1514 → 1540
    DUF3652; Huntingtin protein region
    sd00044
    Location:114 → 136
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056059.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    116327379..116449465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060416649.1 → XP_060272632.1  huntingtin isoform X7

    UniProtKB/TrEMBL
    A0AC11C8R3
    Related
    ENSOARP00020098619.1, ENSOART00020100183.1

  2. XM_060416656.1 → XP_060272639.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  3. XM_060416645.1 → XP_060272628.1  huntingtin isoform X3

    UniProtKB/TrEMBL
    A0AC11DMP8

  4. XM_060416648.1 → XP_060272631.1  huntingtin isoform X6

    UniProtKB/TrEMBL
    A0AC11C8R3

  5. XM_060416644.1 → XP_060272627.1  huntingtin isoform X2

    UniProtKB/TrEMBL
    A0AC11C8R3

  6. XM_060416647.1 → XP_060272630.1  huntingtin isoform X5

    UniProtKB/TrEMBL
    A0AC11C8R3

  7. XM_060416643.1 → XP_060272626.1  huntingtin isoform X1

    UniProtKB/TrEMBL
    A0AC11C8R3

  8. XM_060416646.1 → XP_060272629.1  huntingtin isoform X4

    UniProtKB/TrEMBL
    A0AC11C8R3

  9. XM_060416652.1 → XP_060272635.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  10. XM_060416655.1 → XP_060272638.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  11. XM_060416650.1 → XP_060272633.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  12. XM_060416653.1 → XP_060272636.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  13. XM_060416651.1 → XP_060272634.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  14. XM_060416654.1 → XP_060272637.1  huntingtin isoform X8

    UniProtKB/TrEMBL
    A0AC11C8R3

  15. XM_060416657.1 → XP_060272640.1  huntingtin isoform X9

Nucleotide Protein Strain
Heading Accession and Version

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