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gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100216126, updated on 16-Jun-2026
Official Symbol
gnat2provided by Xenbase
Official Full Name
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2provided by Xenbase
Primary source
Xenbase:XB-GENE-6258657
See related
Ensembl:ENSXETG00000002005 AllianceGenome:Xenbase:XB-GENE-6258657
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
achm4; gnatc
Summary
Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm; photoreceptor inner segment; and photoreceptor outer segment. Human ortholog(s) of this gene implicated in achromatopsia 4 and color blindness. Orthologous to human GNAT2 (G protein subunit alpha transducin 2). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
all
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See gnat2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (71654035..71692077, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (63286934..63325120, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene adhesion molecule with Ig-like domain 1 Neighboring gene G protein-coupled receptor 61 Neighboring gene G protein subunit alpha i3 Neighboring gene adenosine monophosphate deaminase 2 Neighboring gene glutathione S-transferase mu 1 Neighboring gene EPS8-like 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
guanine nucleotide-binding protein G(t) subunit alpha-2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142105.1 → NP_001135577.1  guanine nucleotide-binding protein G(t) subunit alpha-2

    See identical proteins and their annotated locations for NP_001135577.1

    Status: PROVISIONAL

    Source sequence(s)
    BC168083
    UniProtKB/TrEMBL
    A0A803KJ22, A0A8J0QCH1
    Related
    ENSXETP00000004299.5, ENSXETT00000004299.5
    Conserved Domains (1) summary
    cd00066
    Location:34 → 348
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    71654035..71692077 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012957458.2 → XP_012812912.1  guanine nucleotide-binding protein G(t) subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8J0SFC5
    Related
    ENSXETP00000073740.2, ENSXETT00000074534.2
    Conserved Domains (1) summary
    cd00066
    Location:1 → 296
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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