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epha4 EPH receptor A4 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100216124, updated on 15-Nov-2019

Summary

Symbol
epha4provided by Xenbase
Full Name
EPH receptor A4provided by Xenbase
Primary source
Xenbase:XB-GENE-1015803
See related
Ensembl:ENSXETG00000001208
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
Pag; sek; hek8; rtk1; sek-1; tyr01; XEpha4; eph-a4; epha4-a; epha4-b; Pagliaccio
Orthologs

Genomic context

See epha4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (121186956..121235356, complement)
102 previous assembly Xtropicalis_v7 (GCF_000004195.2) Unplaced Scaffold NW_004668244.1 (44207784..44256183, complement)

Chromosome 5 - NC_030681.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108647636 Neighboring gene uncharacterized LOC105948434 Neighboring gene uncharacterized LOC101732582 Neighboring gene uncharacterized LOC108647700 Neighboring gene uncharacterized LOC100491450

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Homology

General protein information

Preferred Names
ephrin type-A receptor 4
NP_001135575.1
XP_012825631.1
XP_012825633.1
XP_017949298.1
XP_017949299.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142103.1NP_001135575.1  ephrin type-A receptor 4 precursor

    See identical proteins and their annotated locations for NP_001135575.1

    Status: PROVISIONAL

    Source sequence(s)
    BC168080
    UniProtKB/TrEMBL
    B4F704
    Conserved Domains (9) summary
    cd09545
    Location:910980
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:907974
    SAM; Sterile alpha motif
    cd10482
    Location:30203
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:440531
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07714
    Location:620876
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:547617
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cd05066
    Location:615880
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    cd00185
    Location:293326
    TNFRSF; CRD2 [structural motif]
    cl22855
    Location:273327
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_tropicalis_v9.1 Primary Assembly

Genomic

  1. NC_030681.1 Reference Xenopus_tropicalis_v9.1 Primary Assembly

    Range
    121186956..121235356 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012970179.2XP_012825633.1  ephrin type-A receptor 4 isoform X3

    Related
    ENSXETP00000016770.1, ENSXETT00000006420.1
    Conserved Domains (7) summary
    cd09545
    Location:910980
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:907974
    SAM; Sterile alpha motif
    cd10482
    Location:30203
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:440531
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:615881
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:620877
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:551615
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
  2. XM_012970177.1XP_012825631.1  ephrin type-A receptor 4 isoform X1

    Related
    ENSXETP00000000639.1, ENSXETT00000006596.1
    Conserved Domains (7) summary
    cd09545
    Location:911981
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:908975
    SAM; Sterile alpha motif
    cd10482
    Location:30203
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:440531
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:615881
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:620877
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:551615
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
  3. XM_018093809.1XP_017949298.1  ephrin type-A receptor 4 isoform X2

  4. XM_018093810.1XP_017949299.1  ephrin type-A receptor 4 isoform X4

    Related
    ENSXETP00000016371.1, ENSXETT00000005590.1
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