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ST14 ST14 transmembrane serine protease matriptase [ Pan troglodytes (chimpanzee) ]

Gene ID: 100188950, updated on 7-Apr-2024

Summary

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Official Symbol
ST14provided by VGNC
Official Full Name
ST14 transmembrane serine protease matriptaseprovided by VGNC
Primary source
VGNC:VGNC:3057
Locus tag
CK820_G0015420
See related
Ensembl:ENSPTRG00000004481
Gene type
protein coding
RefSeq status
INFERRED
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See ST14 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (132085365..132136467)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (131301356..131352429)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene elongin-B-like Neighboring gene amyloid beta precursor like protein 2 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC129136493 Neighboring gene zinc finger and BTB domain containing 44 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2-like Neighboring gene ATP-dependent RNA helicase DDX18-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Orthologous numbering of great ape and human chromosomes is essential for comparative genomics. McConkey EH. Cytogenet Genome Res, 2004. PMID 15218271
  2. Initial sequence of the chimpanzee genome and comparison with the human genome. Chimpanzee Sequencing and Analysis Consortium. Nature, 2005 Sep 1. PMID 16136131

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acrosome reaction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of tumorigenicity 14 protein
Names
suppression of tumorigenicity 14 (colon carcinoma)
NP_001189434.2
XP_016775226.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001202505.5 → NP_001189434.2  suppressor of tumorigenicity 14 protein

    Status: INFERRED

    Source sequence(s)
    JAQQLN020000009
    UniProtKB/TrEMBL
    A0A2I3TMM1, A0A2J8N113, A0A6D2XNL0, H2Q547
    Related
    ENSPTRP00000007670.4, ENSPTRT00000008307.4
    Conserved Domains (4) summary
    cd00041
    Location:340 → 446
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00112
    Location:525 → 559
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:615 → 852
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam01390
    Location:88 → 171
    SEA; SEA domain

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    132085365..132136467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016919737.4 → XP_016775226.1  suppressor of tumorigenicity 14 protein isoform X1

    UniProtKB/TrEMBL
    A0A2I3TMM1
Nucleotide Protein
Heading Accession and Version

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