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TOMM6 translocase of outer mitochondrial membrane 6 [ Homo sapiens (human) ]

Gene ID: 100188893, updated on 6-Nov-2022

Summary

Official Symbol
TOMM6provided by HGNC
Official Full Name
translocase of outer mitochondrial membrane 6provided by HGNC
Primary source
HGNC:HGNC:34528
See related
Ensembl:ENSG00000214736 MIM:616168; AllianceGenome:HGNC:34528
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OBTP; TOM6
Summary
Predicted to be involved in protein transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal (RPKM 63.4), kidney (RPKM 57.9) and 25 other tissues See more
Orthologs
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Genomic context

See TOMM6 in Genome Data Viewer
Location:
6p21.1
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (41787694..41789895)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (41616256..41618460)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (41755432..41757633)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene prickle planar cell polarity protein 4 Neighboring gene Sharpr-MPRA regulatory region 15280 Neighboring gene ubiquitin specific peptidase 49 Neighboring gene small nucleolar RNA SNORA8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32622, DKFZp761H221

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrial outer membrane TAS
Traceable Author Statement
more info
 
part_of mitochondrial outer membrane translocase complex IC
Inferred by Curator
more info
PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
mitochondrial import receptor subunit TOM6 homolog
Names
over-expressed breast tumor protein
overexpressed breast tumor protein
translocase of outer membrane 6 kDa subunit homolog
translocase of outer mitochondrial membrane 6 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134493.2NP_001127965.1  mitochondrial import receptor subunit TOM6 homolog

    See identical proteins and their annotated locations for NP_001127965.1

    Status: REVIEWED

    Source sequence(s)
    AL365205
    Consensus CDS
    CCDS47424.1
    UniProtKB/Swiss-Prot
    Q96B49, Q9UH52
    Related
    ENSP00000381859.3, ENST00000398884.7
    Conserved Domains (1) summary
    pfam15184
    Location:174
    TOM6p; Mitochondrial import receptor subunit TOM6 homolog
  2. NM_001382294.1NP_001369223.1  mitochondrial import receptor subunit TOM6 homolog

    Status: REVIEWED

    Source sequence(s)
    AL365205
    Consensus CDS
    CCDS47424.1
    UniProtKB/Swiss-Prot
    Q9UH52
    Related
    ENSP00000381856.3, ENST00000398881.4
    Conserved Domains (1) summary
    pfam15184
    Location:174
    TOM6p; Mitochondrial import receptor subunit TOM6 homolog

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    41787694..41789895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    41616256..41618460
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)