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mirlet7a-2 microRNA let-7a-2 [ Ciona intestinalis (vase tunicate) ]

Gene ID: 100187688, updated on 26-Oct-2021
Gene symbol
mirlet7a-2
Gene description
microRNA let-7a-2
See related
miRBase:MI0007150
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Ciona intestinalis
Lineage
Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
Also known as
mirnlet7a-2; cin-let-7a-2
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See mirlet7a-2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
104 current KH (GCF_000224145.3) 4 NC_020169.2 (2158324..2158433)

Chromosome 4 - NC_020169.2Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase HUWE1-like Neighboring gene microRNA let-7f Neighboring gene microRNA let-7b Neighboring gene transmembrane protein 145-like Neighboring gene mitochondrial import inner membrane translocase subunit Tim29-like Neighboring gene uncharacterized LOC104265611

Genomic Sequence:
NC_020169.2 Chromosome 4 Reference KH Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Altered miRNA repertoire in the simplified chordate, Oikopleura dioica. Fu X, et al. Mol Biol Evol, 2008 Jun. PMID 18339653
  2. miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data. Hendrix D, et al. Genome Biol, 2010. PMID 20370911, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Other Names

  • microRNA 7a-2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_032328.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    EAAA01001944

RefSeqs of Annotated Genomes: Ciona intestinalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference KH Primary Assembly

Genomic

  1. NC_020169.2 Reference KH Primary Assembly

    Range
    2158324..2158433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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