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NEU1 neuraminidase 1 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100172668, updated on 26-Mar-2024

Summary

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Gene symbol
NEU1
Gene description
neuraminidase 1
Locus tag
CR201_G0054015
See related
Ensembl:ENSPPYG00000036759
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 5 NC_071990.2 (32073833..32077657, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 6 NC_071991.1 (32020784..32024608, complement)

Chromosome 5 - NC_071990.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103890866 Neighboring gene small nucleolar RNA SNORD52 Neighboring gene small nucleolar RNA ZL8 Neighboring gene solute carrier family 44 member 4 Neighboring gene euchromatic histone lysine methyltransferase 2 Neighboring gene complement C2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • DKFZp459L0538, DKFZp468K0928, DKFZp469E1532

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables exo-alpha-sialidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ganglioside catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in oligosaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sialidase-1
Names
N-acetyl-alpha-neuraminidase 1
acetylneuraminyl hydrolase
lysosomal sialidase
sialidase 1 (lysosomal sialidase)
NP_001125743.1
NP_001128939.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001132271.1 → NP_001125743.1  sialidase-1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001125743.1

    Status: PROVISIONAL

    Source sequence(s)
    CR859063
    UniProtKB/Swiss-Prot
    Q5RA14, Q5RAF4, Q5RF22
    UniProtKB/TrEMBL
    A0A8I5UQB4
    Related
    ENSPPYP00000027731.1, ENSPPYT00000059078.1
    Conserved Domains (1) summary
    cd15482
    Location:62 → 410
    Sialidase_non-viral; Non-viral sialidases

  2. NM_001135467.1 → NP_001128939.1  sialidase-1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001128939.1

    Status: PROVISIONAL

    Source sequence(s)
    CR859212
    UniProtKB/TrEMBL
    A0A2J8R4I3
    Conserved Domains (1) summary
    cd15482
    Location:62 → 267
    Sialidase_non-viral; Non-viral sialidases

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071990.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    32073833..32077657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RAF4.1 GenPept UniProtKB/Swiss-Prot:Q5RAF4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Miscellaneous