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NR4A1 nuclear receptor subfamily 4 group A member 1 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100172457, updated on 3-Apr-2024

Summary

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Gene symbol
NR4A1
Gene description
nuclear receptor subfamily 4 group A member 1
Locus tag
CR201_G0039405
See related
Ensembl:ENSPPYG00000004537
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 10 NC_071995.2 (49800565..49822861)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 12 NC_071997.1 (49801457..49823733)

Chromosome 10 - NC_071995.2Genomic Context describing neighboring genes Neighboring gene activin A receptor type 1B Neighboring gene U6 spliceosomal RNA Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene uncharacterized LOC134759502 Neighboring gene autophagy related 101 Neighboring gene olfactory receptor 7E24-like Neighboring gene small integral membrane protein 41

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • DKFZp468J136

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear glucocorticoid receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to corticotropin-releasing hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear receptor subfamily 4immunitygroup A member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001132073.1 → NP_001125545.1  nuclear receptor subfamily 4immunitygroup A member 1

    See identical proteins and their annotated locations for NP_001125545.1

    Status: PROVISIONAL

    Source sequence(s)
    CR858741
    UniProtKB/TrEMBL
    A0A2J8SXM8, Q5RBB0
    Related
    ENSPPYP00000005178.1, ENSPPYT00000005380.2
    Conserved Domains (2) summary
    cd07348
    Location:361 → 598
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:265 → 339
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071995.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    49800565..49822861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009247735.4 → XP_009246010.2  nuclear receptor subfamily 4immunitygroup A member 1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8SXM8, A0A8I5YLP3
    Related
    ENSPPYP00000032872.1
    Conserved Domains (2) summary
    cd07348
    Location:432 → 669
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:336 → 410
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

  2. XM_054526358.2 → XP_054382333.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8SXM1, A0A2J8SXM4, K7EVR2

  3. XM_024256106.3 → XP_024111874.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X3

    UniProtKB/TrEMBL
    A0A2J8SXM8, A0A6D2W2V0
    Related
    ENSPPYP00000024648.2
    Conserved Domains (3) summary
    cd07348
    Location:374 → 611
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:278 → 352
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B
    pfam15694
    Location:148 → 243
    Med26_M; Mediator complex subunit 26 middle domain

  4. XM_009247736.4 → XP_009246011.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X4

    UniProtKB/TrEMBL
    A0A2J8SXL8, A0A2J8SXM8, A0A6D2Y6P8, H2NHC6
    Conserved Domains (3) summary
    cd07348
    Location:361 → 598
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:265 → 339
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B
    pfam15694
    Location:135 → 230
    Med26_M; Mediator complex subunit 26 middle domain

  5. XM_063711555.1 → XP_063567625.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X4

    UniProtKB/TrEMBL
    A0A2J8SXL8, A0A6D2Y6P8, H2NHC6
Nucleotide Protein
Heading Accession and Version

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