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EPOP elongin BC and polycomb repressive complex 2 associated protein [ Homo sapiens (human) ]

Gene ID: 100170841, updated on 13-Mar-2020

Summary

Official Symbol
EPOPprovided by HGNC
Official Full Name
elongin BC and polycomb repressive complex 2 associated proteinprovided by HGNC
Primary source
HGNC:HGNC:34493
See related
Ensembl:ENSG00000273604 MIM:617795
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRR28; C17orf96
Orthologs

Genomic context

See EPOP in Genome Data Viewer
Location:
17q12
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (38671703..38674957, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (36827956..36831187, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene SRC kinase signaling inhibitor 1 Neighboring gene uncharacterized LOC105371761 Neighboring gene Sharpr-MPRA regulatory region 2012 Neighboring gene uncharacterized LOC105371764 Neighboring gene uncharacterized LOC105371763 Neighboring gene microRNA 4734

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
histone H2B conserved C-terminal lysine deubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
stem cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
colocalizes_with ESC/E(Z) complex ISS
Inferred from Sequence or Structural Similarity
more info
 
chromosome IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with elongin complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
elongin BC and Polycomb repressive complex 2-associated protein
Names
proline rich 28
proline-rich protein 28
uncharacterized protein C17orf96

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130677.2NP_001124149.1  elongin BC and Polycomb repressive complex 2-associated protein

    See identical proteins and their annotated locations for NP_001124149.1

    Status: VALIDATED

    Source sequence(s)
    AC006449
    Consensus CDS
    CCDS45661.1
    UniProtKB/Swiss-Prot
    A6NHQ4
    Related
    ENSP00000484710.1, ENST00000621654.2
    Conserved Domains (1) summary
    pfam15223
    Location:305371
    DUF4584; Domain of unknown function (DUF4584)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    38671703..38674957 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187614.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    2707022..2710276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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