U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tedc2 tubulin epsilon and delta complex 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100158225, updated on 5-Sep-2025
Official Symbol
Tedc2provided by RGD
Official Full Name
tubulin epsilon and delta complex 2provided by RGD
Primary source
RGD:2293499
See related
Ensembl:ENSRNOG00000007436 AllianceGenome:RGD:2293499
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in positive regulation of smoothened signaling pathway. Predicted to be located in centriole and cilium. Orthologous to human TEDC2 (tubulin epsilon and delta complex 2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Thymus (RPKM 25.9), Spleen (RPKM 24.7) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See Tedc2 in Genome Data Viewer
Location:
10q12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13750586..13755775, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (13246032..13251196, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (13586852..13591938, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 24 Neighboring gene uncharacterized LOC102551327 Neighboring gene netrin 3 Neighboring gene cyclin F Neighboring gene ATP-binding cassette, subfamily A (ABC1), member 17 Neighboring gene uncharacterized LOC134480760

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Breslow DK, et al. Nat Genet, 2018 Mar. PMID 29459677, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC188077

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in positive regulation of smoothened signaling pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
located_in cilium ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
tubulin epsilon and delta complex protein 2
Names
uncharacterized protein C16orf59 homolog

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127606.1 → NP_001121078.1  tubulin epsilon and delta complex protein 2

    See identical proteins and their annotated locations for NP_001121078.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166509
    UniProtKB/TrEMBL
    A6HCR0, B2GV34
    Related
    ENSRNOP00000046320.4, ENSRNOT00000047734.6
    Conserved Domains (1) summary
    pfam15764
    Location:151 → 432
    DUF4693; Domain of unknown function (DUF4693)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    13750586..13755775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084981.2 → XP_038940909.1  tubulin epsilon and delta complex protein 2 isoform X1

    Conserved Domains (1) summary
    pfam15764
    Location:66 → 298
    DUF4693; Domain of unknown function (DUF4693)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools