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HEXA hexosaminidase subunit alpha [ Ovis aries (sheep) ]

Gene ID: 100145856, updated on 10-Feb-2026
Gene symbol
HEXA
Gene description
hexosaminidase subunit alpha
See related
Ensembl:ENSOARG00020097194
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See HEXA in Genome Data Viewer
Location:
chromosome: 7
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 7 NC_056060.1 (19104364..19135657, complement)

Chromosome 7 - NC_056060.1Genomic Context describing neighboring genes Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene CUGBP Elav-like family member 6 Neighboring gene uncharacterized LOC132660159 Neighboring gene NADH dehydrogenase (ubiquinone) complex I, assembly factor 6-like Neighboring gene transfer RNA lysine (anticodon UUU)

Genomic Sequence:
NC_056060.1 Chromosome 7 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Ovis aries Rambouillet Genome sequencing and assembly
  • BioProject: PRJNA414087
  • Analysis date: Thu Jan 09 10:41:41 2025

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-N-acetylhexosaminidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ganglioside catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycosaminoglycan metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
beta-hexosaminidase subunit alpha
Names
hexosaminidase A (alpha polypeptide)
NP_001119815.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126343.1 → NP_001119815.1  beta-hexosaminidase subunit alpha precursor

    See identical proteins and their annotated locations for NP_001119815.1

    Status: PROVISIONAL

    Source sequence(s)
    EU579459
    UniProtKB/TrEMBL
    A0A6P3CWX9, A0AC11DYS6, B2LSM6
    Related
    ENSOARP00020092336.1, ENSOART00020151622.1
    Conserved Domains (2) summary
    cd06562
    Location:167 → 511
    GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
    pfam14845
    Location:23 → 145
    Glycohydro_20b2; beta-acetyl hexosaminidase like

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056060.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    19104364..19135657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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