lama5 laminin subunit alpha 5 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: lama5provided by Xenbase
Official Full Name: laminin subunit alpha 5provided by Xenbase
Primary source: Xenbase:XB-GENE-1007923
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 80

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	10	NC_030686.2 (4570556..4654435, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	10	NC_030686.1 (1317593..1389339, complement)

Chromosome 10 - NC_030686.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell migration	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of embryonic development	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in basement membrane	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: laminin subunit alpha-5

Names: laminin, alpha 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

4570556..4654435 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018097871.2 → XP_017953360.2 laminin subunit alpha-5 isoform X3

UniProtKB/TrEMBL

A0A8J0T6M7

Conserved Domains (11) summary

pfam03302
Location:1732 → 2037

VSP; Giardia variant-specific surface protein

PTZ00121
Location:2200 → 2501

PTZ00121; MAEBL; Provisional

smart00180
Location:1961 → 2005

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00282
Location:2669 → 2801

LamG; Laminin G domain

cd00055
Location:1469 → 1519

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3411 → 3560

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2081 → 2338

Laminin_I; Laminin Domain I

pfam06009
Location:2523 → 2651

Laminin_II; Laminin Domain II

pfam00052
Location:1582 → 1719

Laminin_B; Laminin B (Domain IV)

pfam00053
Location:1331 → 1379

Laminin_EGF; Laminin EGF domain

pfam00055
Location:34 → 281

Laminin_N; Laminin N-terminal (Domain VI)
XM_012952648.3 → XP_012808102.2 laminin subunit alpha-5 isoform X2

UniProtKB/TrEMBL

A0A8J0S5D1

Conserved Domains (11) summary

pfam03302
Location:1777 → 2082

VSP; Giardia variant-specific surface protein

PTZ00121
Location:2245 → 2546

PTZ00121; MAEBL; Provisional

smart00180
Location:2006 → 2050

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00282
Location:2714 → 2846

LamG; Laminin G domain

cd00055
Location:1514 → 1564

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3456 → 3605

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2126 → 2383

Laminin_I; Laminin Domain I

pfam06009
Location:2568 → 2696

Laminin_II; Laminin Domain II

pfam00052
Location:1627 → 1764

Laminin_B; Laminin B (Domain IV)

pfam00053
Location:1376 → 1424

Laminin_EGF; Laminin EGF domain

pfam00055
Location:34 → 281

Laminin_N; Laminin N-terminal (Domain VI)
XM_012952647.3 → XP_012808101.2 laminin subunit alpha-5 isoform X1

UniProtKB/TrEMBL

A0A8J0S9J6

Conserved Domains (11) summary

pfam03302
Location:1823 → 2128

VSP; Giardia variant-specific surface protein

PTZ00121
Location:2291 → 2592

PTZ00121; MAEBL; Provisional

smart00180
Location:2052 → 2096

EGF_Lam; Laminin-type epidermal growth factor-like domai

smart00282
Location:2760 → 2892

LamG; Laminin G domain

cd00055
Location:661 → 704

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:3502 → 3651

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam06008
Location:2172 → 2429

Laminin_I; Laminin Domain I

pfam06009
Location:2614 → 2742

Laminin_II; Laminin Domain II

pfam00052
Location:1673 → 1810

Laminin_B; Laminin B (Domain IV)

pfam00053
Location:1422 → 1470

Laminin_EGF; Laminin EGF domain

pfam00055
Location:34 → 281

Laminin_N; Laminin N-terminal (Domain VI)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001127133.1: Suppressed sequence

Description

NM_001127133.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: LAMA5 (GeneID:3911).