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psip1 PC4 and SFRS1 interacting protein 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100145476, updated on 6-Jul-2026
Official Symbol
psip1provided by Xenbase
Official Full Name
PC4 and SFRS1 interacting protein 1provided by Xenbase
Primary source
Xenbase:XB-GENE-1007137
See related
Ensembl:ENSXETG00000003303 AllianceGenome:Xenbase:XB-GENE-1007137
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
paip; dfs70; ledgf; psip2
Summary
Predicted to enable DNA binding activity. Predicted to be involved in chromatin remodeling. Predicted to be active in nucleus. Orthologous to human PSIP1 (PC4 and SRSF1 interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Try the new Transcripts and proteins table
See psip1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (123931104..123955725)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (111706115..111730736)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene leucine rich repeat and Ig domain containing 2 Neighboring gene uncharacterized LOC116406524 Neighboring gene small nuclear RNA activating complex polypeptide 3 Neighboring gene tetratricopeptide repeat domain 39B

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
PC4 and SFRS1-interacting protein

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126928.1 → NP_001120400.1  PC4 and SFRS1-interacting protein

    See identical proteins and their annotated locations for NP_001120400.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161115
    UniProtKB/TrEMBL
    A0A8J0QCI3, B1H2S8
    Related
    ENSXETP00000097616.2, ENSXETT00000070262.2
    Conserved Domains (2) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    pfam11467
    Location:383 → 484
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    123931104..123955725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012956209.3 → XP_012811663.1  PC4 and SFRS1-interacting protein isoform X2

    UniProtKB/TrEMBL
    A0A8J0SEA4
    Conserved Domains (2) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    pfam11467
    Location:406 → 507
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  2. XM_012956207.3 → XP_012811661.1  PC4 and SFRS1-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_012811661.1

    UniProtKB/TrEMBL
    A0A8J0S6U9
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:267 → 572
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:407 → 500
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  3. XM_012956206.3 → XP_012811660.1  PC4 and SFRS1-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_012811660.1

    UniProtKB/TrEMBL
    A0A8J0S6U9
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:267 → 572
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:407 → 500
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  4. XM_012956211.3 → XP_012811665.1  PC4 and SFRS1-interacting protein isoform X4

    UniProtKB/TrEMBL
    A0A8J0S6V3
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:105 → 548
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:383 → 476
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  5. XM_012956213.3 → XP_012811667.1  PC4 and SFRS1-interacting protein isoform X5

    See identical proteins and their annotated locations for XP_012811667.1

    UniProtKB/TrEMBL
    A0A6I8SIT5
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:228 → 533
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:368 → 461
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  6. XM_012956205.3 → XP_012811659.1  PC4 and SFRS1-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_012811659.1

    UniProtKB/TrEMBL
    A0A8J0S6U9
    Related
    ENSXETP00000068180.2, ENSXETT00000088041.2
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:267 → 572
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:407 → 500
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  7. XM_012956212.3 → XP_012811666.1  PC4 and SFRS1-interacting protein isoform X5

    See identical proteins and their annotated locations for XP_012811666.1

    UniProtKB/TrEMBL
    A0A6I8SIT5
    Related
    ENSXETP00000093108.1, ENSXETT00000066986.2
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:228 → 533
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:368 → 461
    LEDGF; Lens epithelium-derived growth factor (LEDGF)

  8. XM_012956210.3 → XP_012811664.1  PC4 and SFRS1-interacting protein isoform X3

    UniProtKB/TrEMBL
    F6TAG8
    Related
    ENSXETP00000007169.5, ENSXETT00000007169.5
    Conserved Domains (3) summary
    cd05834
    Location:3 → 87
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PTZ00121
    Location:252 → 386
    PTZ00121; MAEBL; Provisional
    pfam11467
    Location:384 → 477
    LEDGF; Lens epithelium-derived growth factor (LEDGF)
Nucleotide Protein Strain
Heading Accession and Version

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