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elf3 E74 like ETS transcription factor 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100144720, updated on 23-Apr-2026
Official Symbol
elf3provided by Xenbase
Official Full Name
E74 like ETS transcription factor 3provided by Xenbase
Primary source
Xenbase:XB-GENE-853529
See related
Ensembl:ENSXETG00000031510 AllianceGenome:Xenbase:XB-GENE-853529
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
ert; esx; epr-1; ese-1
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human ELF3 (E74 like ETS transcription factor 3). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See elf3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (72738917..72745388, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (64373907..64380374, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene retinoblastoma binding protein 5 Neighboring gene G protein-coupled receptor 37 like 1 Neighboring gene arginyl aminopeptidase (aminopeptidase B) Neighboring gene mitochondrial pyruvate carrier 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
ETS-related transcription factor Elf-3
Names
E74-like factor 3 (ets domain transcription factor, epithelial-specific)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    72738917..72745388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002932989.5 → XP_002933035.1  ETS-related transcription factor Elf-3

    UniProtKB/TrEMBL
    A0A6I8PX17, A0A803J5P5
    Related
    ENSXETP00000060398.2, ENSXETT00000064683.3
    Conserved Domains (2) summary
    smart00413
    Location:281 → 368
    ETS; erythroblast transformation specific domain
    cl15755
    Location:62 → 138
    SAM_superfamily; SAM (Sterile alpha motif )
Nucleotide Protein Strain
Heading Accession and Version

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