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itgav integrin subunit alpha V [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100144691, updated on 8-Mar-2024

Summary

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Official Symbol
itgavprovided by Xenbase
Official Full Name
integrin subunit alpha Vprovided by Xenbase
Primary source
Xenbase:XB-GENE-488969
See related
Ensembl:ENSXETG00000013317
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
cd51; msk8; vnra; itgav-a; itgav-b
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
30
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (46057806..46257238)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (37714089..37912307)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 15 Neighboring gene uncharacterized LOC116407730 Neighboring gene calcitonin receptor like receptor Neighboring gene MOB family member 4, phocein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
integrin alpha-V
Names
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123449.1 → NP_001116921.1  integrin alpha-V

    See identical proteins and their annotated locations for NP_001116921.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161515
    UniProtKB/TrEMBL
    A0A6I8T290, B1WAV5
    Related
    ENSXETP00000029208.5, ENSXETT00000029208.5
    Conserved Domains (4) summary
    smart00191
    Location:233 → 288
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:880 → 894
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:334 → 777
    Integrin_alpha2; Integrin alpha
    sd00039
    Location:54 → 107
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    46057806..46257238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012970033.3 → XP_012825487.1  integrin alpha-V isoform X1

    UniProtKB/TrEMBL
    A0A6I8QC93, A0A6I8RDD4, F7A493
    Related
    ENSXETP00000078916.2, ENSXETT00000071804.2
    Conserved Domains (4) summary
    smart00191
    Location:356 → 411
    Int_alpha; Integrin alpha (beta-propellor repeats)
    sd00039
    Location:177 → 230
    7WD40; WD40 repeat [structural motif]
    pfam00357
    Location:1003 → 1017
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:457 → 900
    Integrin_alpha2; Integrin alpha
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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