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shmt2 serine hydroxymethyltransferase 2 (mitochondrial) [ Danio rerio (zebrafish) ]

Gene ID: 100144628, updated on 12-Aug-2018

Summary

Official Symbol
shmt2provided by ZNC
Official Full Name
serine hydroxymethyltransferase 2 (mitochondrial)provided by ZNC
Primary source
ZFIN:ZDB-GENE-071213-1
See related
Ensembl:ENSDARG00000104414
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Orthologs

Genomic context

See shmt2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (59176470..59230818)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (59182239..59235373)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 9 Neighboring gene neurexophilin 4 Neighboring gene NDUFA4, mitochondrial complex associated like 2 Neighboring gene family with sequence similarity 210, member B

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
amino acid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
cobalt ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycine hydroxymethyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycine hydroxymethyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
serine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
L-serine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to tetrahydrofolate IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
folic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycine biosynthetic process from serine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 
glycine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
methylation IEA
Inferred from Electronic Annotation
more info
 
one-carbon metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein homotetramerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of oxidative phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 
tetrahydrofolate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
BRISC complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
serine hydroxymethyltransferase, mitochondrial
Names
mitochondrial serine hydroxymethyltransferase
NP_001116846.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123374.1NP_001116846.1  serine hydroxymethyltransferase, mitochondrial

    See identical proteins and their annotated locations for NP_001116846.1

    Status: PROVISIONAL

    Source sequence(s)
    EF213101
    UniProtKB/TrEMBL
    A9LDD9
    Related
    ENSDARP00000132340.2, ENSDART00000161720.2
    Conserved Domains (2) summary
    PLN03226
    Location:34489
    PLN03226; serine hydroxymethyltransferase; Provisional
    pfam00464
    Location:38436
    SHMT; Serine hydroxymethyltransferase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    59176470..59230818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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