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STAT6 signal transducer and activator of transcription 6 [ Canis lupus familiaris (dog) ]

Gene ID: 100142679, updated on 18-Sep-2020

Summary

Official Symbol
STAT6provided by VGNC
Official Full Name
signal transducer and activator of transcription 6provided by VGNC
Primary source
VGNC:VGNC:46892
See related
Ensembl:ENSCAFG00000000163
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs

Genomic context

See STAT6 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
24
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 10 NC_006592.3 (1232515..1247011, complement)

Chromosome 10 - NC_006592.3Genomic Context describing neighboring genes Neighboring gene tachykinin precursor 3 Neighboring gene nuclear envelope integral membrane protein 1 Neighboring gene NGFI-A binding protein 2 Neighboring gene LDL receptor related protein 1 Neighboring gene neurexophilin 4

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006592.3 Chromosome 10 Reference CanFam3.1 Primary Assembly

Pathways from PubChem

General gene information

Markers

Homology

General protein information

Preferred Names
signal transducer and activator of transcription 6
Names
signal transducer and activator of transcription 6, interleukin-4 induced

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001314102.1NP_001301031.1  signal transducer and activator of transcription 6

    Status: PROVISIONAL

    Source sequence(s)
    BK006461
    UniProtKB/TrEMBL
    A0A0I9QQS7
    Related
    ENSCAFP00000047819.1, ENSCAFT00000070839.1
    Conserved Domains (5) summary
    cd10377
    Location:489618
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    pfam01017
    Location:96243
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:245498
    STAT_bind; STAT protein, DNA binding domain
    pfam14596
    Location:627816
    STAT6_C; STAT6 C-terminal
    cl03749
    Location:2122
    STAT_int; STAT protein, protein interaction domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006592.3 Reference CanFam3.1 Primary Assembly

    Range
    1232515..1247011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003431442.4XP_003431490.1  signal transducer and activator of transcription 6 isoform X1

    See identical proteins and their annotated locations for XP_003431490.1

    UniProtKB/TrEMBL
    F1PAY3
    Related
    ENSCAFP00000046565.1, ENSCAFT00000069415.1
    Conserved Domains (5) summary
    cd10377
    Location:517646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2115
    STAT_int; STAT protein, protein interaction domain
    pfam14596
    Location:655844
    STAT6_C; STAT6 C-terminal
    pfam01017
    Location:124271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273526
    STAT_bind; STAT protein, DNA binding domain
  2. XM_022423971.1XP_022279679.1  signal transducer and activator of transcription 6 isoform X1

    Conserved Domains (5) summary
    cd10377
    Location:517646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2115
    STAT_int; STAT protein, protein interaction domain
    pfam14596
    Location:655844
    STAT6_C; STAT6 C-terminal
    pfam01017
    Location:124271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273526
    STAT_bind; STAT protein, DNA binding domain
  3. XM_005625532.3XP_005625589.1  signal transducer and activator of transcription 6 isoform X1

    See identical proteins and their annotated locations for XP_005625589.1

    UniProtKB/TrEMBL
    F1PAY3
    Related
    ENSCAFP00000000244.2, ENSCAFT00000000269.3
    Conserved Domains (5) summary
    cd10377
    Location:517646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2115
    STAT_int; STAT protein, protein interaction domain
    pfam14596
    Location:655844
    STAT6_C; STAT6 C-terminal
    pfam01017
    Location:124271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273526
    STAT_bind; STAT protein, DNA binding domain
  4. XM_022423970.1XP_022279678.1  signal transducer and activator of transcription 6 isoform X1

    Conserved Domains (5) summary
    cd10377
    Location:517646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2115
    STAT_int; STAT protein, protein interaction domain
    pfam14596
    Location:655844
    STAT6_C; STAT6 C-terminal
    pfam01017
    Location:124271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273526
    STAT_bind; STAT protein, DNA binding domain
  5. XM_022423969.1XP_022279677.1  signal transducer and activator of transcription 6 isoform X1

    Conserved Domains (5) summary
    cd10377
    Location:517646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2115
    STAT_int; STAT protein, protein interaction domain
    pfam14596
    Location:655844
    STAT6_C; STAT6 C-terminal
    pfam01017
    Location:124271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273526
    STAT_bind; STAT protein, DNA binding domain
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