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LY6E-DT LY6E divergent transcript [ Homo sapiens (human) ]

Gene ID: 100133669, updated on 10-Dec-2024

Summary

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Official Symbol
LY6E-DTprovided by HGNC
Official Full Name
LY6E divergent transcriptprovided by HGNC
Primary source
HGNC:HGNC:53728
See related
AllianceGenome:HGNC:53728
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in brain (RPKM 2.8), liver (RPKM 1.1) and 14 other tissues See more
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Genomic context

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See LY6E-DT in Genome Data Viewer
Location:
8q24.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (142982031..143018390, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (144125816..144162087, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (144063448..144099807, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene CYP11B2 recombination region Neighboring gene CYP11B2 promoter Neighboring gene cytochrome P450 family 11 subfamily B member 2 Neighboring gene uncharacterized LOC105375794 Neighboring gene Sharpr-MPRA regulatory region 5092 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144033761-144034332 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:144063636-144063766 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144070153-144070654 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144073720-144074227 Neighboring gene CDC42 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144089139-144089952 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144089953-144090765 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144104683-144105446 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144105447-144106208 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144106209-144106972 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144107735-144108497 Neighboring gene uncharacterized LOC124902034 Neighboring gene lymphocyte antigen 6 family member E

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma. Guan Z, et al. Cell Prolif, 2020 Apr. PMID 32130753, Free PMC Article
  2. Functional prediction of long non-coding RNAs in ovarian cancer-associated fibroblasts indicate a potential role in metastasis. Vafaee F, et al. Sci Rep, 2017 Sep 4. PMID 28871211, Free PMC Article
  3. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
  4. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Fei T, et al. Proc Natl Acad Sci U S A, 2017 Jun 27. PMID 28611215, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Clone Names

  • MGC15613

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_026913.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BM557790

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    142982031..143018390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187573.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    2188..8718 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001756307.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    144125816..144162087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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