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KRTAP4-7 keratin associated protein 4-7 [ Homo sapiens (human) ]

Gene ID: 100132476, updated on 23-Nov-2021

Summary

Official Symbol
KRTAP4-7provided by HGNC
Official Full Name
keratin associated protein 4-7provided by HGNC
Primary source
HGNC:HGNC:18898
See related
Ensembl:ENSG00000240871
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KAP4.7; KRTAP4.7
Summary
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Mar 2009]
Orthologs
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Genomic context

See KRTAP4-7 in Genome Data Viewer
Location:
17q21.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (41084150..41085144)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39240459..39241396)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin associated protein 2-4 Neighboring gene keratin associated protein 2-5, pseudogene Neighboring gene keratin associated protein 4-8 Neighboring gene keratin associated protein 4-16

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC161699, MGC161701

General protein information

Preferred Names
putative keratin-associated protein 4-X
Names
Ultrahigh sulfur keratin-associated protein 4.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033061.4NP_149050.3  putative keratin-associated protein 4-X

    Status: VALIDATED

    Source sequence(s)
    AC100808
    Consensus CDS
    CCDS45673.1
    Related
    ENSP00000375236.4, ENST00000391417.5
    Conserved Domains (2) summary
    pfam01500
    Location:3154
    Keratin_B2; Keratin, high sulfur B2 protein
    pfam13885
    Location:4488
    Keratin_B2_2; Keratin, high sulfur B2 protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    41084150..41085144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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