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ZNF316 zinc finger protein 316 [ Homo sapiens (human) ]

Gene ID: 100131017, updated on 13-May-2022

Summary

Official Symbol
ZNF316provided by HGNC
Official Full Name
zinc finger protein 316provided by HGNC
Primary source
HGNC:HGNC:13843
See related
Ensembl:ENSG00000205903 AllianceGenome:HGNC:13843
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MZF-3
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in spleen (RPKM 6.9), fat (RPKM 4.9) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF316 in Genome Data Viewer
Location:
7p22.1
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (6637318..6658279)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (6756509..6777459)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (6676949..6697910)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 15 Neighboring gene Sharpr-MPRA regulatory region 9377 Neighboring gene zinc finger protein 853 Neighboring gene Sharpr-MPRA regulatory region 15225 Neighboring gene uncharacterized LOC124901583 Neighboring gene zinc finger protein 33B pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686B2320

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278559.2NP_001265488.1  zinc finger protein 316

    See identical proteins and their annotated locations for NP_001265488.1

    Status: VALIDATED

    Source sequence(s)
    AC073343
    Consensus CDS
    CCDS75563.1
    UniProtKB/Swiss-Prot
    A6NFI3
    Related
    ENSP00000477706.1, ENST00000382252.6
    Conserved Domains (4) summary
    smart00349
    Location:158218
    KRAB; krueppel associated box
    COG5048
    Location:746933
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:833853
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:705730
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    6637318..6658279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024446618.2XP_024302386.1  zinc finger protein 316 isoform X1

    Conserved Domains (4) summary
    smart00349
    Location:158218
    KRAB; krueppel associated box
    COG5048
    Location:746933
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:833853
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:705730
    zf-H2C2_2; Zinc-finger double domain
  2. XM_024446619.2XP_024302387.1  zinc finger protein 316 isoform X1

    Conserved Domains (4) summary
    smart00349
    Location:158218
    KRAB; krueppel associated box
    COG5048
    Location:746933
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:833853
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:705730
    zf-H2C2_2; Zinc-finger double domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    6756509..6777459
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)