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TMEM221 transmembrane protein 221 [ Homo sapiens (human) ]

Gene ID: 100130519, updated on 23-Nov-2021

Summary

Official Symbol
TMEM221provided by HGNC
Official Full Name
transmembrane protein 221provided by HGNC
Primary source
HGNC:HGNC:21943
See related
Ensembl:ENSG00000188051
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in ovary (RPKM 1.6), adrenal (RPKM 1.1) and 16 other tissues See more
Orthologs
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Genomic context

See TMEM221 in Genome Data Viewer
Location:
19p13.11
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (17435509..17448839, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (17546318..17559477, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene multivesicular body subunit 12A Neighboring gene BST2 interferon stimulated positive regulator Neighboring gene high mobility group box 3 pseudogene 29 Neighboring gene nucleoredoxin like 1 Neighboring gene solute carrier family 27 member 1 Neighboring gene Sharpr-MPRA regulatory region 2801

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 221
Names
Putative transmembrane protein ENSP00000342162

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190844.2NP_001177773.1  transmembrane protein 221

    See identical proteins and their annotated locations for NP_001177773.1

    Status: VALIDATED

    Source sequence(s)
    AC010319, BY797043
    Consensus CDS
    CCDS54230.1
    UniProtKB/Swiss-Prot
    A6NGB7
    Related
    ENSP00000342162.5, ENST00000341130.6
    Conserved Domains (1) summary
    pfam15038
    Location:32186
    Jiraiya; Jiraiya

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    17435509..17448839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527603.2XP_011525905.1  transmembrane protein 221 isoform X1

    See identical proteins and their annotated locations for XP_011525905.1

    Conserved Domains (1) summary
    pfam15038
    Location:32186
    Jiraiya; Jiraiya
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