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TCF24 transcription factor 24 [ Homo sapiens (human) ]

Gene ID: 100129654, updated on 5-Aug-2022

Summary

Official Symbol
TCF24provided by HGNC
Official Full Name
transcription factor 24provided by HGNC
Primary source
HGNC:HGNC:32275
See related
Ensembl:ENSG00000261787 AllianceGenome:HGNC:32275
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TCF-24; bHLHa25
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See TCF24 in Genome Data Viewer
Location:
8q13.1
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (66946501..66962591, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (67372982..67389072, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (67858736..67874826, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene C8orf44-SGK3 readthrough Neighboring gene serum/glucocorticoid regulated kinase family member 3 Neighboring gene pituitary tumor-transforming 3, pseudogene Neighboring gene minichromosome maintenance domain containing 2 Neighboring gene small nucleolar RNA, C/D box 87 Neighboring gene small nucleolar RNA host gene 6 Neighboring gene pre-mRNA processing factor 3 pseudogene Neighboring gene protein phosphatase 1 regulatory subunit 42 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in developmental process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193502.2NP_001180431.1  transcription factor 24

    See identical proteins and their annotated locations for NP_001180431.1

    Status: VALIDATED

    Source sequence(s)
    AC110998, AW028708, CX788264
    Consensus CDS
    CCDS59103.1
    UniProtKB/Swiss-Prot
    H3BPR9, Q7RTU0
    Related
    ENSP00000455444.1, ENST00000563496.2
    Conserved Domains (1) summary
    smart00353
    Location:56107
    HLH; helix loop helix domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    66946501..66962591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    67372982..67389072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)