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Gpr153 G protein-coupled receptor 153 [ Mus musculus (house mouse) ]

Gene ID: 100129, updated on 26-Sep-2022

Summary

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Official Symbol
Gpr153provided by MGI
Official Full Name
G protein-coupled receptor 153provided by MGI
Primary source
MGI:MGI:1916157
See related
Ensembl:ENSMUSG00000042804 AllianceGenome:MGI:1916157
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PGR1; 1110065N12Rik
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including craniocervical region bone; esophagus; heart valve; neural retina; and submandibular gland primordium mesenchyme. Orthologous to human GPR153 (G protein-coupled receptor 153). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 45.3), mammary gland adult (RPKM 24.8) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Gpr153 in Genome Data Viewer
Location:
4; 4 E2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (152358563..152369798)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (152274106..152285342)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30622 Neighboring gene acyl-CoA thioesterase 7 Neighboring gene hes family bHLH transcription factor 3 Neighboring gene isoprenylcysteine carboxyl methyltransferase Neighboring gene RIKEN cDNA 9430083M05 gene Neighboring gene ring finger protein 207 Neighboring gene ribosomal protein L22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The G protein-coupled receptor repertoires of human and mouse. Vassilatis DK, et al. Proc Natl Acad Sci U S A, 2003 Apr 15. PMID 12679517, Free PMC Article
  2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (13) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable G-protein coupled receptor 153
Names
G protein-coupled receptor PGR1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001374784.1 → NP_001361713.1  probable G-protein coupled receptor 153 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL611985
    Consensus CDS
    CCDS89864.1
    UniProtKB/TrEMBL
    A2A8K5
    Related
    ENSMUSP00000101275.2, ENSMUST00000105650.8
    Conserved Domains (2) summary
    cd14964
    Location:9 → 35
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:8 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. NM_178406.2 → NP_848493.1  probable G-protein coupled receptor 153 isoform 1

    See identical proteins and their annotated locations for NP_848493.1

    Status: VALIDATED

    Source sequence(s)
    AL611985
    Consensus CDS
    CCDS18996.1
    UniProtKB/Swiss-Prot
    Q8CFK0, Q8K0Z9
    Related
    ENSMUSP00000101276.2, ENSMUST00000105651.8
    Conserved Domains (3) summary
    PHA03247
    Location:359 → 587
    PHA03247; large tegument protein UL36; Provisional
    cd14964
    Location:10 → 34
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:8 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    152358563..152369798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250170.3 → XP_011248472.1  probable G-protein coupled receptor 153 isoform X1

    Conserved Domains (3) summary
    PHA03247
    Location:299 → 527
    PHA03247; large tegument protein UL36; Provisional
    cd14964
    Location:9 → 35
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:8 → 248
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K0Z9.2 GenPept UniProtKB/Swiss-Prot:Q8K0Z9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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