cenpo centromere protein O [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cenpoprovided by ZNC
Official Full Name: centromere protein Oprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070928-16
See related: Ensembl:ENSDARG00000075619 AllianceGenome:ZFIN:ZDB-GENE-070928-16
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:171667
Summary: Predicted to act upstream of or within centromere complex assembly. Predicted to be located in kinetochore and nucleus. Predicted to be part of Mis6-Sim4 complex. Orthologous to human CENPO (centromere protein O). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	17	NC_133192.1 (7665314..7673188, complement)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (6528067..6535941, complement)

Chromosome 17 - NC_133192.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within centromere complex assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Mis6-Sim4 complex	IBA Inferred from Biological aspect of Ancestor more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: centromere protein O

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.