U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TBK1 TANK binding kinase 1 [ Sus scrofa (pig) ]

Gene ID: 100125828, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
TBK1provided by VGNC
Official Full Name
TANK binding kinase 1provided by VGNC
Primary source
VGNC:VGNC:93787
See related
Ensembl:ENSSSCG00000031103
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in lung (RPKM 10.3), spleen (RPKM 8.7) and 8 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
21
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (28880210..28929964)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003540499.1 (192..1751)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene KICSTOR subunit 2 Neighboring gene chromosome 5 C12orf56 homolog Neighboring gene exportin for tRNA Neighboring gene Ras association domain family member 3 Neighboring gene glucosamine (N-acetyl)-6-sulfatase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Classical swine fever virus non-structural protein 4B binds tank-binding kinase 1. Lv H, et al. J Biosci, 2018 Dec. PMID 30541955
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Classical swine fever virus non-structural protein 4B binds TBK1.
    Title: Classical swine fever virus non-structural protein 4B binds tank-binding kinase 1.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serine/threonine-protein kinase TBK1
Names
NF-kappa-B-activating kinase
serine/threonine protein kinase TBK1
NP_001098762.1
XP_020946511.1
XP_020946512.1
XP_020946513.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105292.1 → NP_001098762.1  serine/threonine-protein kinase TBK1

    See identical proteins and their annotated locations for NP_001098762.1

    Status: PROVISIONAL

    Source sequence(s)
    EU091339
    UniProtKB/TrEMBL
    A0A287AL42, A0A4X1W422, A0A8D1B5F0, A0A8D1J7T4, A7UNK0
    Related
    ENSSSCP00000066069.1, ENSSSCT00000077604.2
    Conserved Domains (2) summary
    cd12219
    Location:297 → 385
    UBL_TBK1_like; Ubiquitin-Like Domain Of Human Tbk1 and similar proteins
    cd13988
    Location:15 → 330
    STKc_TBK1; Catalytic domain of the Serine/Threonine kinase, TANK Binding Kinase 1

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    28880210..28929964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021090852.1 → XP_020946511.1  serine/threonine-protein kinase TBK1 isoform X1

    UniProtKB/TrEMBL
    A0A287AL42, A0A4X1W422, A0A8D1B5F0, A0A8D1J7T4, A7UNK0
    Related
    ENSSSCP00000032011.3, ENSSSCT00000061881.3
    Conserved Domains (2) summary
    cd12219
    Location:297 → 385
    UBL_TBK1_like; Ubiquitin-Like Domain Of Human Tbk1 and similar proteins
    cd13988
    Location:15 → 330
    STKc_TBK1; Catalytic domain of the Serine/Threonine kinase, TANK Binding Kinase 1

  2. XM_021090853.1 → XP_020946512.1  serine/threonine-protein kinase TBK1 isoform X1

    UniProtKB/TrEMBL
    A0A287AL42, A0A4X1W422, A0A8D1B5F0, A0A8D1J7T4, A7UNK0
    Conserved Domains (2) summary
    cd12219
    Location:297 → 385
    UBL_TBK1_like; Ubiquitin-Like Domain Of Human Tbk1 and similar proteins
    cd13988
    Location:15 → 330
    STKc_TBK1; Catalytic domain of the Serine/Threonine kinase, TANK Binding Kinase 1

  3. XM_021090854.1 → XP_020946513.1  serine/threonine-protein kinase TBK1 isoform X2

    UniProtKB/TrEMBL
    A0A8D0MNM8, A0A8D1QHM9, A0A8D1ZZ43
    Related
    ENSSSCP00000039751.3, ENSSSCT00000062705.3
    Conserved Domains (3) summary
    cd12219
    Location:175 → 263
    UBL_TBK1_like; Ubiquitin-Like Domain Of Human Tbk1 and similar proteins
    cl21453
    Location:1 → 208
    PKc_like; Protein Kinases, catalytic domain
    cl28204
    Location:366 → 536
    GlgA; Glycogen synthase [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.