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LIG4 DNA ligase 4 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100084171, updated on 8-Mar-2024

Summary

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Gene symbol
LIG4
Gene description
DNA ligase 4
See related
Ensembl:ENSOANG00000015936
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
2
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 20 NC_041747.1 (10439145..10446668, complement)

Chromosome 20 - NC_041747.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114805855 Neighboring gene abhydrolase domain containing 13 Neighboring gene uncharacterized LOC103170471 Neighboring gene laccase domain containing 1 Neighboring gene TNF superfamily member 13b Neighboring gene small nucleolar RNA SNORA7 Neighboring gene myosin XVI

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041747.1 Chromosome 20 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA ligase (ATP) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA ligation involved in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via nonhomologous end joining IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunoglobulin V(D)J recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair, DNA gap filling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA ligase IV complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of DNA-dependent protein kinase-DNA ligase 4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA ligase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041747.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    10439145..10446668 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007668657.3 → XP_007666847.2  DNA ligase 4

    UniProtKB/TrEMBL
    A0A6I8NQ56
    Conserved Domains (4) summary
    TIGR00574
    Location:79 → 600
    dnl1; DNA ligase I, ATP-dependent (dnl1)
    pfam11411
    Location:747 → 780
    DNA_ligase_IV; DNA ligase IV
    cd17717
    Location:810 → 897
    BRCT_DNA_ligase_IV_rpt2; second BRCT domain of DNA ligase 4 (LIG4) and similar proteins
    cd17722
    Location:655 → 742
    BRCT_DNA_ligase_IV_rpt1; first BRCT domain of DNA ligase 4 (LIG4) and similar proteins
Nucleotide Protein
Heading Accession and Version

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