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folr folate receptor [ Danio rerio (zebrafish) ]

Gene ID: 100073336, updated on 9-Dec-2024

Summary

Official Symbol
folrprovided by ZNC
Official Full Name
folate receptorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070615-23
See related
Ensembl:ENSDARG00000102442 AllianceGenome:ZFIN:ZDB-GENE-070615-23
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:165502
Summary
Predicted to enable signaling receptor activity. Acts upstream of or within type B pancreatic cell differentiation. Predicted to be active in external side of plasma membrane. Is expressed in cloaca; head; heart; and pectoral fin. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Orthologous to several human genes including FOLR1 (folate receptor alpha); FOLR2 (folate receptor beta); and FOLR3 (folate receptor gamma). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See folr in Genome Data Viewer
Location:
chromosome: 15
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (47342124..47349065)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (46903511..46910452)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487690 Neighboring gene anaphase promoting complex subunit 15 Neighboring gene mitogen-activated protein kinase kinase kinase kinase 1 Neighboring gene ClpB family mitochondrial disaggregase

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables fructose 1,6-bisphosphate 1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within type B pancreatic cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
folate receptor
NP_001092242.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098772.1NP_001092242.1  folate receptor precursor

    See identical proteins and their annotated locations for NP_001092242.1

    Status: PROVISIONAL

    Source sequence(s)
    BC142824
    UniProtKB/TrEMBL
    A5PLB2
    Related
    ENSDARP00000140245.1, ENSDART00000162092.3
    Conserved Domains (1) summary
    pfam03024
    Location:28203
    Folate_rec; Folate receptor family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    47342124..47349065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)