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PAK1 p21 (RAC1) activated kinase 1 [ Equus caballus (horse) ]

Gene ID: 100063217, updated on 8-Mar-2024

Summary

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Official Symbol
PAK1provided by VGNC
Official Full Name
p21 (RAC1) activated kinase 1provided by VGNC
Primary source
VGNC:VGNC:56770
See related
Ensembl:ENSECAG00000017840
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
18
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 7 NC_009150.3 (69042881..69175376)
102 previous assembly EquCab2.0 (GCF_000002305.2) 7 NC_009150.2 (66921942..66996294)

Chromosome 7 - NC_009150.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111774329 Neighboring gene aquaporin 11 Neighboring gene uncharacterized LOC111774330 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 4 Neighboring gene uncharacterized LOC111774331 Neighboring gene myosin VIIA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009150.3 Reference EquCab3.0 Primary Assembly

    Range
    69042881..69175376
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023645654.1 → XP_023501422.1  serine/threonine-protein kinase PAK 1

    UniProtKB/TrEMBL
    A0A9L0RVD0, F7AM77
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  2. XM_014741764.2 → XP_014597250.1  serine/threonine-protein kinase PAK 1

    UniProtKB/TrEMBL
    A0A9L0RVD0, F7AM77
    Related
    ENSECAP00000016091.1, ENSECAT00000019645.4
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  3. XM_001917175.5 → XP_001917210.1  serine/threonine-protein kinase PAK 1

    See identical proteins and their annotated locations for XP_001917210.1

    UniProtKB/TrEMBL
    A0A9L0RVD0, F7AM77
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  4. XM_014741765.2 → XP_014597251.1  serine/threonine-protein kinase PAK 1

    UniProtKB/TrEMBL
    A0A9L0RVD0, F7AM77
    Related
    ENSECAP00000067765.1, ENSECAT00000102484.1
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  5. XM_023645655.1 → XP_023501423.1  serine/threonine-protein kinase PAK 1

    UniProtKB/TrEMBL
    A0A9L0RVD0, F7AM77
    Conserved Domains (2) summary
    cd06654
    Location:248 → 543
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain
Nucleotide Protein
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