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TMPRSS2 transmembrane serine protease 2 [ Equus caballus (horse) ]

Gene ID: 100058498, updated on 14-Jan-2019

Summary

Official Symbol
TMPRSS2provided by VGNC
Official Full Name
transmembrane serine protease 2provided by VGNC
Primary source
VGNC:VGNC:24341
See related
Ensembl:ENSECAG00000022289
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs

Genomic context

See TMPRSS2 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
16
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 26 NC_009169.3 (38356375..38390295, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 26 NC_009169.2 (37095503..37128807, complement)

Chromosome 26 - NC_009169.3Genomic Context describing neighboring genes Neighboring gene MX dynamin like GTPase 2 Neighboring gene MX dynamin like GTPase 1 Neighboring gene uncharacterized LOC102149405 Neighboring gene keratin-associated protein 10-3 Neighboring gene keratin-associated protein 12-1-like Neighboring gene receptor interacting serine/threonine kinase 4

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General protein information

Preferred Names
transmembrane protease serine 2
Names
transmembrane protease, serine 2

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009169.3 Reference EquCab3.0 Primary Assembly

    Range
    38356375..38390295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005606160.3XP_005606217.1  transmembrane protease serine 2

    Conserved Domains (3) summary
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:254484
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:153248
    SRCR_2; Scavenger receptor cysteine-rich domain
  2. XM_023630207.1XP_023485975.1  transmembrane protease serine 2

    Conserved Domains (3) summary
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:254484
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:153248
    SRCR_2; Scavenger receptor cysteine-rich domain
  3. XM_014736385.2XP_014591871.1  transmembrane protease serine 2

    Related
    ENSECAP00000020029.2, ENSECAT00000024126.2
    Conserved Domains (3) summary
    cd00112
    Location:113148
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:254484
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam15494
    Location:153248
    SRCR_2; Scavenger receptor cysteine-rich domain
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